APPARATUS AND METHODS FOR INTEGRATED SAMPLE PREPARATION, REACTION AND DETECTION
Cartridges for the isolation of a biological sample and downstream biological assays on the sample are provided. In one embodiment, a nucleic acid sample is isolated from a biological sample and the nucleic acid sample is amplified, for example by the polymerase chain reaction. The cartridges provid...
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| creator | CHING, JESUS RICHARDSON, BRUCE JOHNSON, BRUCE A MORAVICK, KEITH E BIRD, DYLAN HILMER |
| description | Cartridges for the isolation of a biological sample and downstream biological assays on the sample are provided. In one embodiment, a nucleic acid sample is isolated from a biological sample and the nucleic acid sample is amplified, for example by the polymerase chain reaction. The cartridges provided herein can also be used for the isolation of non- nucleic acid samples, for example proteins, and to perform downstream reactions on the proteins, for example, binding assays. Instruments for carrying out the downstream biological assays and for detecting the results of the assays are also provided.
Des cartouches disolement dun échantillon biologique et dessais biologiques en aval sur léchantillon sont décrites. Dans un mode de réalisation, un échantillon dacide nucléique est isolé dun échantillon biologique et léchantillon dacide nucléique est amplifié, par exemple par réaction en chaîne de la polymérase. Les cartouches fournies ci-inclus peuvent également être utilisées pour lisolement déchantillons qui ne sont pas à base dacides nucléiques, par exemple de protéines, et pour effectuer des réactions en aval sur les protéines, par exemple, des essais de liaison. Des instruments de conduite dessais biologiques en aval et de détection des résultats des essais sont également décrits. |
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Des cartouches disolement dun échantillon biologique et dessais biologiques en aval sur léchantillon sont décrites. Dans un mode de réalisation, un échantillon dacide nucléique est isolé dun échantillon biologique et léchantillon dacide nucléique est amplifié, par exemple par réaction en chaîne de la polymérase. Les cartouches fournies ci-inclus peuvent également être utilisées pour lisolement déchantillons qui ne sont pas à base dacides nucléiques, par exemple de protéines, et pour effectuer des réactions en aval sur les protéines, par exemple, des essais de liaison. Des instruments de conduite dessais biologiques en aval et de détection des résultats des essais sont également décrits.</description><language>eng ; fre</language><subject>APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY ; BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS OR TEST PAPERS THEREFOR ; COMPOSITIONS THEREOF ; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ; CULTURE MEDIA ; ENZYMOLOGY ; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE ; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES ; MEASURING ; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING ; MUTATION OR GENETIC ENGINEERING ; PERFORMING OPERATIONS ; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL ; PHYSICS ; PROCESSES OF PREPARING SUCH COMPOSITIONS ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; TESTING ; TRANSPORTING ; VINEGAR ; WINE</subject><creationdate>2020</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20200804&DB=EPODOC&CC=CA&NR=2977845C$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,777,882,25545,76296</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20200804&DB=EPODOC&CC=CA&NR=2977845C$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>CHING, JESUS</creatorcontrib><creatorcontrib>RICHARDSON, BRUCE</creatorcontrib><creatorcontrib>JOHNSON, BRUCE A</creatorcontrib><creatorcontrib>MORAVICK, KEITH E</creatorcontrib><creatorcontrib>BIRD, DYLAN HILMER</creatorcontrib><title>APPARATUS AND METHODS FOR INTEGRATED SAMPLE PREPARATION, REACTION AND DETECTION</title><description>Cartridges for the isolation of a biological sample and downstream biological assays on the sample are provided. In one embodiment, a nucleic acid sample is isolated from a biological sample and the nucleic acid sample is amplified, for example by the polymerase chain reaction. The cartridges provided herein can also be used for the isolation of non- nucleic acid samples, for example proteins, and to perform downstream reactions on the proteins, for example, binding assays. Instruments for carrying out the downstream biological assays and for detecting the results of the assays are also provided.
Des cartouches disolement dun échantillon biologique et dessais biologiques en aval sur léchantillon sont décrites. Dans un mode de réalisation, un échantillon dacide nucléique est isolé dun échantillon biologique et léchantillon dacide nucléique est amplifié, par exemple par réaction en chaîne de la polymérase. Les cartouches fournies ci-inclus peuvent également être utilisées pour lisolement déchantillons qui ne sont pas à base dacides nucléiques, par exemple de protéines, et pour effectuer des réactions en aval sur les protéines, par exemple, des essais de liaison. Des instruments de conduite dessais biologiques en aval et de détection des résultats des essais sont également décrits.</description><subject>APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY</subject><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS OR TEST PAPERS THEREFOR</subject><subject>COMPOSITIONS THEREOF</subject><subject>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE</subject><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</subject><subject>MEASURING</subject><subject>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PERFORMING OPERATIONS</subject><subject>PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL</subject><subject>PHYSICS</subject><subject>PROCESSES OF PREPARING SUCH COMPOSITIONS</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>TESTING</subject><subject>TRANSPORTING</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2020</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZPB3DAhwDHIMCQ1WcPRzUfB1DfHwdwlWcPMPUvD0C3F1B0q5uigEO_oG-LgqBAS5ghV7-vvpKAS5OjqDWGB9Lq4hrmAeDwNrWmJOcSovlOZmkHdzDXH20E0tyI9PLS5ITE7NSy2Jd3Y0sjQ3tzAxdTYmrAIAjNgt8A</recordid><startdate>20200804</startdate><enddate>20200804</enddate><creator>CHING, JESUS</creator><creator>RICHARDSON, BRUCE</creator><creator>JOHNSON, BRUCE A</creator><creator>MORAVICK, KEITH E</creator><creator>BIRD, DYLAN HILMER</creator><scope>EVB</scope></search><sort><creationdate>20200804</creationdate><title>APPARATUS AND METHODS FOR INTEGRATED SAMPLE PREPARATION, REACTION AND DETECTION</title><author>CHING, JESUS ; RICHARDSON, BRUCE ; JOHNSON, BRUCE A ; MORAVICK, KEITH E ; BIRD, DYLAN HILMER</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CA2977845C3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2020</creationdate><topic>APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY</topic><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS OR TEST PAPERS THEREFOR</topic><topic>COMPOSITIONS THEREOF</topic><topic>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE</topic><topic>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</topic><topic>MEASURING</topic><topic>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PERFORMING OPERATIONS</topic><topic>PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL</topic><topic>PHYSICS</topic><topic>PROCESSES OF PREPARING SUCH COMPOSITIONS</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>TESTING</topic><topic>TRANSPORTING</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>CHING, JESUS</creatorcontrib><creatorcontrib>RICHARDSON, BRUCE</creatorcontrib><creatorcontrib>JOHNSON, BRUCE A</creatorcontrib><creatorcontrib>MORAVICK, KEITH E</creatorcontrib><creatorcontrib>BIRD, DYLAN HILMER</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>CHING, JESUS</au><au>RICHARDSON, BRUCE</au><au>JOHNSON, BRUCE A</au><au>MORAVICK, KEITH E</au><au>BIRD, DYLAN HILMER</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>APPARATUS AND METHODS FOR INTEGRATED SAMPLE PREPARATION, REACTION AND DETECTION</title><date>2020-08-04</date><risdate>2020</risdate><abstract>Cartridges for the isolation of a biological sample and downstream biological assays on the sample are provided. In one embodiment, a nucleic acid sample is isolated from a biological sample and the nucleic acid sample is amplified, for example by the polymerase chain reaction. The cartridges provided herein can also be used for the isolation of non- nucleic acid samples, for example proteins, and to perform downstream reactions on the proteins, for example, binding assays. Instruments for carrying out the downstream biological assays and for detecting the results of the assays are also provided.
Des cartouches disolement dun échantillon biologique et dessais biologiques en aval sur léchantillon sont décrites. Dans un mode de réalisation, un échantillon dacide nucléique est isolé dun échantillon biologique et léchantillon dacide nucléique est amplifié, par exemple par réaction en chaîne de la polymérase. Les cartouches fournies ci-inclus peuvent également être utilisées pour lisolement déchantillons qui ne sont pas à base dacides nucléiques, par exemple de protéines, et pour effectuer des réactions en aval sur les protéines, par exemple, des essais de liaison. Des instruments de conduite dessais biologiques en aval et de détection des résultats des essais sont également décrits.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING MUTATION OR GENETIC ENGINEERING PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL PHYSICS PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS TESTING TRANSPORTING VINEGAR WINE |
| title | APPARATUS AND METHODS FOR INTEGRATED SAMPLE PREPARATION, REACTION AND DETECTION |
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