TAMPER-RESISTANT DOSAGE FORM COMPRISING A POLYETHYLENE GLYCOL GRAFT COPOLYMER

The invention relates to a tamper -resistant, oral pharmaceutical dosage form comprising a pharmacologically active ingredient having psychotropic action and a polyethylene glycol graft copolymer, wherein the content of the polyethylene glycol graft copolymer is at least 25 wt.-%, relative to the to...

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description The invention relates to a tamper -resistant, oral pharmaceutical dosage form comprising a pharmacologically active ingredient having psychotropic action and a polyethylene glycol graft copolymer, wherein the content of the polyethylene glycol graft copolymer is at least 25 wt.-%, relative to the total weight of the pharmaceutical dosage form. The invention also relates to the manufacture of the dosage form and its use. La présente invention concerne une forme pharmaceutique orale inviolable comprenant une substance pharmacologiquement active ayant une action psychotrope et un copolymère greffé par polyéthylène glycol, dans laquelle la teneur du copolymère greffé par polyéthylène glycol est d'au moins 25 % en poids, par rapport au poids total de la forme pharmaceutique. L'invention concerne en outre la fabrication de la forme pharmaceutique et son utilisation.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title TAMPER-RESISTANT DOSAGE FORM COMPRISING A POLYETHYLENE GLYCOL GRAFT COPOLYMER
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