COMMERCIALLY VIABLE SYNTHESIS OF CANTHARIDIN AND BIOACTIVE CANTHARIDIN DERIVATIVES

The present disclosure provides processes for synthesizing cantharidin and cantharidin derivatives. These processes may comprise providing a first compound of formula (1): forming a second compound having formula (2) from said first compound: performing a cycloaddition reaction on said second compou...

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Hauptverfasser: SCHOW, STEVEN R, DAVIDSON, MATTHEW
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creator SCHOW, STEVEN R
DAVIDSON, MATTHEW
description The present disclosure provides processes for synthesizing cantharidin and cantharidin derivatives. These processes may comprise providing a first compound of formula (1): forming a second compound having formula (2) from said first compound: performing a cycloaddition reaction on said second compound to yield a third compound having formula (3): and generating said cantharidin or derivative thereof from said third compound. La présente invention concerne des méthodes de synthèse de la cantharidine et de dérivés de la cantharidine.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title COMMERCIALLY VIABLE SYNTHESIS OF CANTHARIDIN AND BIOACTIVE CANTHARIDIN DERIVATIVES
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