TOSYLATE SALT OF N-[3-[(4AR,7AS)-2-AMINO-6-(5-FLUOROPYRIMIDIN-2-YL)-4,4A,5,7-TETRAHYDROPYRROLO[3,4-D][1,3]THIAZIN-7A-YL]-4I LUORO-PHENYL]-5-METHOXY-PYRAZINE-2-CARBOXAMIDE

The present invention provides a tosylate salt of N-[3-[(4aR,7aS)-2-amino-6-(5-fluoropyrimidin-2-yl)-4,4a,5,7-tetrahydropyrrolo[3,4-d][1,3]thiazin-7a-yl]-4-fluoro-phenyl]-5-methoxy-pyrazine-2-carboxamide and its use in the treatment of Alzheimer's disease. La présente invention concerne un sel...

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Hauptverfasser:	WOLFANGEL, CRAIG DANIEL, COATES, DAVID ANDREW
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator	WOLFANGEL, CRAIG DANIEL COATES, DAVID ANDREW
description	The present invention provides a tosylate salt of N-[3-[(4aR,7aS)-2-amino-6-(5-fluoropyrimidin-2-yl)-4,4a,5,7-tetrahydropyrrolo[3,4-d][1,3]thiazin-7a-yl]-4-fluoro-phenyl]-5-methoxy-pyrazine-2-carboxamide and its use in the treatment of Alzheimer's disease. La présente invention concerne un sel de tosylate de N-[3-[(4aR,7aS)-2-amino-6-(5- fluoropyrimidin-2-yl)-4,4a,5,7-tétrahydropyrrolo[3,4-d][1,3]thiazin-7a-yl]-4-fluoro- phényl]-5-méthoxy-pyrazine-2-carboxamide.
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La présente invention concerne un sel de tosylate de N-[3-[(4aR,7aS)-2-amino-6-(5- fluoropyrimidin-2-yl)-4,4a,5,7-tétrahydropyrrolo[3,4-d][1,3]thiazin-7a-yl]-4-fluoro- phényl]-5-méthoxy-pyrazine-2-carboxamide.</description><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2019</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20190618&DB=EPODOC&CC=CA&NR=2969475C$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76318</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20190618&DB=EPODOC&CC=CA&NR=2969475C$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>WOLFANGEL, CRAIG DANIEL</creatorcontrib><creatorcontrib>COATES, DAVID ANDREW</creatorcontrib><title>TOSYLATE SALT OF N-[3-[(4AR,7AS)-2-AMINO-6-(5-FLUOROPYRIMIDIN-2-YL)-4,4A,5,7-TETRAHYDROPYRROLO[3,4-D][1,3]THIAZIN-7A-YL]-4I LUORO-PHENYL]-5-METHOXY-PYRAZINE-2-CARBOXAMIDE</title><description>The present invention provides a tosylate salt of N-[3-[(4aR,7aS)-2-amino-6-(5-fluoropyrimidin-2-yl)-4,4a,5,7-tetrahydropyrrolo[3,4-d][1,3]thiazin-7a-yl]-4-fluoro-phenyl]-5-methoxy-pyrazine-2-carboxamide and its use in the treatment of Alzheimer's disease. La présente invention concerne un sel de tosylate de N-[3-[(4aR,7aS)-2-amino-6-(5- fluoropyrimidin-2-yl)-4,4a,5,7-tétrahydropyrrolo[3,4-d][1,3]thiazin-7a-yl]-4-fluoro- phényl]-5-méthoxy-pyrazine-2-carboxamide.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2019</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqFjkEKwjAQRbtxIeoZ7FIhs9CmFpdjm5JA2ilpBGMpIhJXooKeylMaxb2rDzPvff4wellqnUYr4ha1jamMa-gS6GYcDcuwncMSsFI1wQpmKZR6S4YaZ1SlClWHp9Nz4IwjS1kGVliD0hVfxJCmLmEcir5bsKS3UuE-OBkGqQeu4m8ZNFLUn0MKlbCSdg6C_CFFqM_RbGgXFhRiHA3Ox8vDT345iqalsLkEf78d_ON-PPmrfx5yXK5Xa56lefKfeAMy1kXk</recordid><startdate>20190618</startdate><enddate>20190618</enddate><creator>WOLFANGEL, CRAIG DANIEL</creator><creator>COATES, DAVID ANDREW</creator><scope>EVB</scope></search><sort><creationdate>20190618</creationdate><title>TOSYLATE SALT OF N-[3-[(4AR,7AS)-2-AMINO-6-(5-FLUOROPYRIMIDIN-2-YL)-4,4A,5,7-TETRAHYDROPYRROLO[3,4-D][1,3]THIAZIN-7A-YL]-4I LUORO-PHENYL]-5-METHOXY-PYRAZINE-2-CARBOXAMIDE</title><author>WOLFANGEL, CRAIG DANIEL ; COATES, DAVID ANDREW</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CA2969475C3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2019</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>WOLFANGEL, CRAIG DANIEL</creatorcontrib><creatorcontrib>COATES, DAVID ANDREW</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>WOLFANGEL, CRAIG DANIEL</au><au>COATES, DAVID ANDREW</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>TOSYLATE SALT OF N-[3-[(4AR,7AS)-2-AMINO-6-(5-FLUOROPYRIMIDIN-2-YL)-4,4A,5,7-TETRAHYDROPYRROLO[3,4-D][1,3]THIAZIN-7A-YL]-4I LUORO-PHENYL]-5-METHOXY-PYRAZINE-2-CARBOXAMIDE</title><date>2019-06-18</date><risdate>2019</risdate><abstract>The present invention provides a tosylate salt of N-[3-[(4aR,7aS)-2-amino-6-(5-fluoropyrimidin-2-yl)-4,4a,5,7-tetrahydropyrrolo[3,4-d][1,3]thiazin-7a-yl]-4-fluoro-phenyl]-5-methoxy-pyrazine-2-carboxamide and its use in the treatment of Alzheimer's disease. La présente invention concerne un sel de tosylate de N-[3-[(4aR,7aS)-2-amino-6-(5- fluoropyrimidin-2-yl)-4,4a,5,7-tétrahydropyrrolo[3,4-d][1,3]thiazin-7a-yl]-4-fluoro- phényl]-5-méthoxy-pyrazine-2-carboxamide.</abstract><oa>free_for_read</oa></addata></record>
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subjects	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title	TOSYLATE SALT OF N-[3-[(4AR,7AS)-2-AMINO-6-(5-FLUOROPYRIMIDIN-2-YL)-4,4A,5,7-TETRAHYDROPYRROLO[3,4-D][1,3]THIAZIN-7A-YL]-4I LUORO-PHENYL]-5-METHOXY-PYRAZINE-2-CARBOXAMIDE
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