TCR LIBRARIES

The present invention relates to a library of particles, the library displaying a plurality of different T cell receptors (TCRs), wherein the plurality of TCRs consists essentially of TCRs comprising an alpha chain variable domain from a natural repertoire and a beta chain variable domain from a nat...

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Hauptverfasser:	VUIDEPOT, ANNELISE BRIGITTE, JAKOBSEN, BENT KARSTEN, LIDDY, NATHANIEL ROSS, MOLLOY, PETER EAMON
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMBINATORIAL CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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creator	VUIDEPOT, ANNELISE BRIGITTE JAKOBSEN, BENT KARSTEN LIDDY, NATHANIEL ROSS MOLLOY, PETER EAMON
description	The present invention relates to a library of particles, the library displaying a plurality of different T cell receptors (TCRs), wherein the plurality of TCRs consists essentially of TCRs comprising an alpha chain variable domain from a natural repertoire and a beta chain variable domain from a natural repertoire, wherein the alpha chain variable10 domain comprises a TRAV12-2 or a TRAV21 gene product and the beta chain variable domain comprises a TRBV6 gene product. La présente invention concerne une banque de particules, la banque présentant une pluralité de différents récepteurs des cellules T (TCR), la pluralité de TCR consistant essentiellement en TCR comprenant un domaine variable de la chaîne alpha provenant d'un répertoire naturel et un domaine variable de la chaîne bêta provenant d'un répertoire naturel, le domaine variable de la chaîne alpha comprenant un produit génique TRAV122 ou TRAV21, et le domaine variable de la chaîne bêta comprenant un produit génique TRBV6.
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La présente invention concerne une banque de particules, la banque présentant une pluralité de différents récepteurs des cellules T (TCR), la pluralité de TCR consistant essentiellement en TCR comprenant un domaine variable de la chaîne alpha provenant d'un répertoire naturel et un domaine variable de la chaîne bêta provenant d'un répertoire naturel, le domaine variable de la chaîne alpha comprenant un produit génique TRAV122 ou TRAV21, et le domaine variable de la chaîne bêta comprenant un produit génique TRBV6.</description><language>eng ; fre</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMBINATORIAL CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; ORGANIC CHEMISTRY ; PEPTIDES ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230801&DB=EPODOC&CC=CA&NR=2942433C$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25544,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230801&DB=EPODOC&CC=CA&NR=2942433C$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>VUIDEPOT, ANNELISE BRIGITTE</creatorcontrib><creatorcontrib>JAKOBSEN, BENT KARSTEN</creatorcontrib><creatorcontrib>LIDDY, NATHANIEL ROSS</creatorcontrib><creatorcontrib>MOLLOY, PETER EAMON</creatorcontrib><title>TCR LIBRARIES</title><description>The present invention relates to a library of particles, the library displaying a plurality of different T cell receptors (TCRs), wherein the plurality of TCRs consists essentially of TCRs comprising an alpha chain variable domain from a natural repertoire and a beta chain variable domain from a natural repertoire, wherein the alpha chain variable10 domain comprises a TRAV12-2 or a TRAV21 gene product and the beta chain variable domain comprises a TRBV6 gene product. La présente invention concerne une banque de particules, la banque présentant une pluralité de différents récepteurs des cellules T (TCR), la pluralité de TCR consistant essentiellement en TCR comprenant un domaine variable de la chaîne alpha provenant d'un répertoire naturel et un domaine variable de la chaîne bêta provenant d'un répertoire naturel, le domaine variable de la chaîne alpha comprenant un produit génique TRAV122 ou TRAV21, et le domaine variable de la chaîne bêta comprenant un produit génique TRBV6.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMBINATORIAL CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2023</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZOANcQ5S8PF0CnIM8nQN5mFgTUvMKU7lhdLcDPJuriHOHrqpBfnxqcUFicmpeakl8c6ORpYmRibGxs7GhFUAADkSG7Y</recordid><startdate>20230801</startdate><enddate>20230801</enddate><creator>VUIDEPOT, ANNELISE BRIGITTE</creator><creator>JAKOBSEN, BENT KARSTEN</creator><creator>LIDDY, NATHANIEL ROSS</creator><creator>MOLLOY, PETER EAMON</creator><scope>EVB</scope></search><sort><creationdate>20230801</creationdate><title>TCR LIBRARIES</title><author>VUIDEPOT, ANNELISE BRIGITTE ; JAKOBSEN, BENT KARSTEN ; LIDDY, NATHANIEL ROSS ; MOLLOY, PETER EAMON</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CA2942433C3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2023</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMBINATORIAL CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>VUIDEPOT, ANNELISE BRIGITTE</creatorcontrib><creatorcontrib>JAKOBSEN, BENT KARSTEN</creatorcontrib><creatorcontrib>LIDDY, NATHANIEL ROSS</creatorcontrib><creatorcontrib>MOLLOY, PETER EAMON</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>VUIDEPOT, ANNELISE BRIGITTE</au><au>JAKOBSEN, BENT KARSTEN</au><au>LIDDY, NATHANIEL ROSS</au><au>MOLLOY, PETER EAMON</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>TCR LIBRARIES</title><date>2023-08-01</date><risdate>2023</risdate><abstract>The present invention relates to a library of particles, the library displaying a plurality of different T cell receptors (TCRs), wherein the plurality of TCRs consists essentially of TCRs comprising an alpha chain variable domain from a natural repertoire and a beta chain variable domain from a natural repertoire, wherein the alpha chain variable10 domain comprises a TRAV12-2 or a TRAV21 gene product and the beta chain variable domain comprises a TRBV6 gene product. 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subjects	BEER BIOCHEMISTRY CHEMISTRY COMBINATORIAL CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
title	TCR LIBRARIES
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