MUSCARINIC RECEPTOR AGONISTS
This invention relates to compounds that are agonists of the muscarinic Mi receptor and which are useful in the treatment of muscarinic Mi receptor mediated diseases. Also provided are pharmaceutical compositions containing the compounds and the therapeutic uses of the compounds. Compounds provided...
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| creator | TEHAN, BENJAMIN GERALD PICKWORTH, MARK BROWN, GILES ALBERT CONGREVE, MILES STUART CANSFIELD, JULIE ELAINE |
| description | This invention relates to compounds that are agonists of the muscarinic Mi receptor and which are useful in the treatment of muscarinic Mi receptor mediated diseases. Also provided are pharmaceutical compositions containing the compounds and the therapeutic uses of the compounds. Compounds provided are of formula where p, q, W, Z Y, X1, x2, R1, rc r-s2, and R4 are as defined herein.
[Formule (1)] L'invention concerne des composés agonistes du récepteur muscarinique M1, qui sont utiles dans le traitement de maladies médiées par le récepteur muscarinique M1. L'invention concerne également des compositions pharmaceutiques contenant les composés et les utilisations thérapeutiques de ces composés. Les composés divulgués sont représentés par une formule, dans laquelle p, q, W, Z Y, X1, X2, R1, R2 et R4 sont tels que définis dans la description. |
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[Formule (1)] L'invention concerne des composés agonistes du récepteur muscarinique M1, qui sont utiles dans le traitement de maladies médiées par le récepteur muscarinique M1. L'invention concerne également des compositions pharmaceutiques contenant les composés et les utilisations thérapeutiques de ces composés. Les composés divulgués sont représentés par une formule, dans laquelle p, q, W, Z Y, X1, X2, R1, R2 et R4 sont tels que définis dans la description.</description><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220531&DB=EPODOC&CC=CA&NR=2942187C$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220531&DB=EPODOC&CC=CA&NR=2942187C$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>TEHAN, BENJAMIN GERALD</creatorcontrib><creatorcontrib>PICKWORTH, MARK</creatorcontrib><creatorcontrib>BROWN, GILES ALBERT</creatorcontrib><creatorcontrib>CONGREVE, MILES STUART</creatorcontrib><creatorcontrib>CANSFIELD, JULIE ELAINE</creatorcontrib><title>MUSCARINIC RECEPTOR AGONISTS</title><description>This invention relates to compounds that are agonists of the muscarinic Mi receptor and which are useful in the treatment of muscarinic Mi receptor mediated diseases. Also provided are pharmaceutical compositions containing the compounds and the therapeutic uses of the compounds. Compounds provided are of formula where p, q, W, Z Y, X1, x2, R1, rc r-s2, and R4 are as defined herein.
[Formule (1)] L'invention concerne des composés agonistes du récepteur muscarinique M1, qui sont utiles dans le traitement de maladies médiées par le récepteur muscarinique M1. L'invention concerne également des compositions pharmaceutiques contenant les composés et les utilisations thérapeutiques de ces composés. Les composés divulgués sont représentés par une formule, dans laquelle p, q, W, Z Y, X1, X2, R1, R2 et R4 sont tels que définis dans la description.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZJDxDQ12dgzy9PN0VghydXYNCPEPUnB09_fzDA4J5mFgTUvMKU7lhdLcDPJuriHOHrqpBfnxqcUFicmpeakl8c6ORpYmRoYW5s7GhFUAAAePICU</recordid><startdate>20220531</startdate><enddate>20220531</enddate><creator>TEHAN, BENJAMIN GERALD</creator><creator>PICKWORTH, MARK</creator><creator>BROWN, GILES ALBERT</creator><creator>CONGREVE, MILES STUART</creator><creator>CANSFIELD, JULIE ELAINE</creator><scope>EVB</scope></search><sort><creationdate>20220531</creationdate><title>MUSCARINIC RECEPTOR AGONISTS</title><author>TEHAN, BENJAMIN GERALD ; PICKWORTH, MARK ; BROWN, GILES ALBERT ; CONGREVE, MILES STUART ; CANSFIELD, JULIE ELAINE</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CA2942187C3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2022</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>TEHAN, BENJAMIN GERALD</creatorcontrib><creatorcontrib>PICKWORTH, MARK</creatorcontrib><creatorcontrib>BROWN, GILES ALBERT</creatorcontrib><creatorcontrib>CONGREVE, MILES STUART</creatorcontrib><creatorcontrib>CANSFIELD, JULIE ELAINE</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>TEHAN, BENJAMIN GERALD</au><au>PICKWORTH, MARK</au><au>BROWN, GILES ALBERT</au><au>CONGREVE, MILES STUART</au><au>CANSFIELD, JULIE ELAINE</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>MUSCARINIC RECEPTOR AGONISTS</title><date>2022-05-31</date><risdate>2022</risdate><abstract>This invention relates to compounds that are agonists of the muscarinic Mi receptor and which are useful in the treatment of muscarinic Mi receptor mediated diseases. Also provided are pharmaceutical compositions containing the compounds and the therapeutic uses of the compounds. Compounds provided are of formula where p, q, W, Z Y, X1, x2, R1, rc r-s2, and R4 are as defined herein.
[Formule (1)] L'invention concerne des composés agonistes du récepteur muscarinique M1, qui sont utiles dans le traitement de maladies médiées par le récepteur muscarinique M1. L'invention concerne également des compositions pharmaceutiques contenant les composés et les utilisations thérapeutiques de ces composés. Les composés divulgués sont représentés par une formule, dans laquelle p, q, W, Z Y, X1, X2, R1, R2 et R4 sont tels que définis dans la description.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | MUSCARINIC RECEPTOR AGONISTS |
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