BETA-HAIRPIN PEPTIDES HAVING ANTI-VIRAL PROPERTIES AGAINST THE DENGUE VIRUS
The invention relates to structurally constrained synthetic peptides that have been optimised to form a beta-hairpin structure. The peptides can inhibit or reduce the infection caused by the dengue virus (DENV). The invention also relates to pharmaceutical compositions containing these synthetic pep...
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| creator | CHINEA SANTIAGO, GLAY GUIROLA CRUZ, OSMANY GARAY PEREZ, HILDA ELISA HUERTA GALINDO, VIVIAN VAZQUEZ CASTILLO, MARIELA REYES ACOSTA, OSVALDO GONZALEZ BLANCO, SONIA MARTIN DUNN, ALEJANDRO MIGUEL MARQUEZ PERERA, GABRIEL JESUS GONZALEZ LOPEZ, LUIS JAVIER YERO DIAZ, ALEXIS FALCON CAMA, VIVIANA GARATEIX SUAREZ, ROCIO ALVAREZ PEREZ, KAREN PUPO GOMEZ, DIANNE SARRIA NUNEZ, MONICA |
| description | The invention relates to structurally constrained synthetic peptides that have been optimised to form a beta-hairpin structure. The peptides can inhibit or reduce the infection caused by the dengue virus (DENV). The invention also relates to pharmaceutical compositions containing these synthetic peptides, said pharmaceutical compositions being suitable for preventing and/or treating the infections caused by DENV. Furthermore, the invention provides a method for treating the infections caused by this virus. |
| format | Patent |
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The peptides can inhibit or reduce the infection caused by the dengue virus (DENV). The invention also relates to pharmaceutical compositions containing these synthetic peptides, said pharmaceutical compositions being suitable for preventing and/or treating the infections caused by DENV. 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The peptides can inhibit or reduce the infection caused by the dengue virus (DENV). The invention also relates to pharmaceutical compositions containing these synthetic peptides, said pharmaceutical compositions being suitable for preventing and/or treating the infections caused by DENV. Furthermore, the invention provides a method for treating the infections caused by this virus.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | BETA-HAIRPIN PEPTIDES HAVING ANTI-VIRAL PROPERTIES AGAINST THE DENGUE VIRUS |
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