NOVEL ASSAY TO DETECT HUMAN PERIOSTIN
This disclosure provides a robust, sensitive, and specific assay for the detection and measurement of periostin levels in samples obtained from human patients having, or suspected of having an IL-13-mediated disease or disorder. The disclosure further provides novel antiperiostin monoclonal antibodi...
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| creator | DILLE, BRUCE VARKEY, REENA PARKER, MELISSA BROPHY, SUSAN LEE, YEN-WAH STREICHER, KATIE YAO, YIHONG DAVIS, GERARD GRANT, ETHAN GREENLEES, LYDIA CHOWDHURY, PARTHA RANADE, KOUSTUBH JEANBLANC, NICOLETTE LIANG, MEINA |
| description | This disclosure provides a robust, sensitive, and specific assay for the detection and measurement of periostin levels in samples obtained from human patients having, or suspected of having an IL-13-mediated disease or disorder. The disclosure further provides novel antiperiostin monoclonal antibodies that recognize at least isoforms 1, 2, 3, 4, 7, and 8 of human periostin, and assay kits comprising one or more of these antibodies.
La présente invention concerne un essai biologique robuste, sensible, et spécifique pour la détection et la mesure de niveaux de la périostine dans des échantillons obtenus à partir de patients humains atteints, ou suspectés d'être atteints par une maladie ou d'un trouble provoqué(e) par l'IL -13. L'invention concerne également de nouveaux anticorps monoclonaux anti-périostine qui reconnaissent au moins des isoformes 1, 2, 3, 4, 7 et 8 de la périostine humaine, et des trousses d'essai biologique comportant un ou plusieurs de ces anticorps. |
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La présente invention concerne un essai biologique robuste, sensible, et spécifique pour la détection et la mesure de niveaux de la périostine dans des échantillons obtenus à partir de patients humains atteints, ou suspectés d'être atteints par une maladie ou d'un trouble provoqué(e) par l'IL -13. L'invention concerne également de nouveaux anticorps monoclonaux anti-périostine qui reconnaissent au moins des isoformes 1, 2, 3, 4, 7 et 8 de la périostine humaine, et des trousses d'essai biologique comportant un ou plusieurs de ces anticorps.</description><language>eng ; fre</language><subject>CHEMISTRY ; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES ; MEASURING ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PHYSICS ; TESTING</subject><creationdate>2015</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20150813&DB=EPODOC&CC=CA&NR=2936285A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20150813&DB=EPODOC&CC=CA&NR=2936285A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>DILLE, BRUCE</creatorcontrib><creatorcontrib>VARKEY, REENA</creatorcontrib><creatorcontrib>PARKER, MELISSA</creatorcontrib><creatorcontrib>BROPHY, SUSAN</creatorcontrib><creatorcontrib>LEE, YEN-WAH</creatorcontrib><creatorcontrib>STREICHER, KATIE</creatorcontrib><creatorcontrib>YAO, YIHONG</creatorcontrib><creatorcontrib>DAVIS, GERARD</creatorcontrib><creatorcontrib>GRANT, ETHAN</creatorcontrib><creatorcontrib>GREENLEES, LYDIA</creatorcontrib><creatorcontrib>CHOWDHURY, PARTHA</creatorcontrib><creatorcontrib>RANADE, KOUSTUBH</creatorcontrib><creatorcontrib>JEANBLANC, NICOLETTE</creatorcontrib><creatorcontrib>LIANG, MEINA</creatorcontrib><title>NOVEL ASSAY TO DETECT HUMAN PERIOSTIN</title><description>This disclosure provides a robust, sensitive, and specific assay for the detection and measurement of periostin levels in samples obtained from human patients having, or suspected of having an IL-13-mediated disease or disorder. The disclosure further provides novel antiperiostin monoclonal antibodies that recognize at least isoforms 1, 2, 3, 4, 7, and 8 of human periostin, and assay kits comprising one or more of these antibodies.
La présente invention concerne un essai biologique robuste, sensible, et spécifique pour la détection et la mesure de niveaux de la périostine dans des échantillons obtenus à partir de patients humains atteints, ou suspectés d'être atteints par une maladie ou d'un trouble provoqué(e) par l'IL -13. L'invention concerne également de nouveaux anticorps monoclonaux anti-périostine qui reconnaissent au moins des isoformes 1, 2, 3, 4, 7 et 8 de la périostine humaine, et des trousses d'essai biologique comportant un ou plusieurs de ces anticorps.</description><subject>CHEMISTRY</subject><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</subject><subject>MEASURING</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PHYSICS</subject><subject>TESTING</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2015</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZFD18w9z9VFwDA52jFQI8VdwcQ1xdQ5R8Aj1dfRTCHAN8vQPDvH042FgTUvMKU7lhdLcDApuriHOHrqpBfnxqcUFicmpeakl8c6ORpbGZkYWpo6GxkQoAQBYkSLP</recordid><startdate>20150813</startdate><enddate>20150813</enddate><creator>DILLE, BRUCE</creator><creator>VARKEY, REENA</creator><creator>PARKER, MELISSA</creator><creator>BROPHY, SUSAN</creator><creator>LEE, YEN-WAH</creator><creator>STREICHER, KATIE</creator><creator>YAO, YIHONG</creator><creator>DAVIS, GERARD</creator><creator>GRANT, ETHAN</creator><creator>GREENLEES, LYDIA</creator><creator>CHOWDHURY, PARTHA</creator><creator>RANADE, KOUSTUBH</creator><creator>JEANBLANC, NICOLETTE</creator><creator>LIANG, MEINA</creator><scope>EVB</scope></search><sort><creationdate>20150813</creationdate><title>NOVEL ASSAY TO DETECT HUMAN PERIOSTIN</title><author>DILLE, BRUCE ; VARKEY, REENA ; PARKER, MELISSA ; BROPHY, SUSAN ; LEE, YEN-WAH ; STREICHER, KATIE ; YAO, YIHONG ; DAVIS, GERARD ; GRANT, ETHAN ; GREENLEES, LYDIA ; CHOWDHURY, PARTHA ; RANADE, KOUSTUBH ; JEANBLANC, NICOLETTE ; LIANG, MEINA</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CA2936285A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2015</creationdate><topic>CHEMISTRY</topic><topic>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</topic><topic>MEASURING</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PHYSICS</topic><topic>TESTING</topic><toplevel>online_resources</toplevel><creatorcontrib>DILLE, BRUCE</creatorcontrib><creatorcontrib>VARKEY, REENA</creatorcontrib><creatorcontrib>PARKER, MELISSA</creatorcontrib><creatorcontrib>BROPHY, SUSAN</creatorcontrib><creatorcontrib>LEE, YEN-WAH</creatorcontrib><creatorcontrib>STREICHER, KATIE</creatorcontrib><creatorcontrib>YAO, YIHONG</creatorcontrib><creatorcontrib>DAVIS, GERARD</creatorcontrib><creatorcontrib>GRANT, ETHAN</creatorcontrib><creatorcontrib>GREENLEES, LYDIA</creatorcontrib><creatorcontrib>CHOWDHURY, PARTHA</creatorcontrib><creatorcontrib>RANADE, KOUSTUBH</creatorcontrib><creatorcontrib>JEANBLANC, NICOLETTE</creatorcontrib><creatorcontrib>LIANG, MEINA</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>DILLE, BRUCE</au><au>VARKEY, REENA</au><au>PARKER, MELISSA</au><au>BROPHY, SUSAN</au><au>LEE, YEN-WAH</au><au>STREICHER, KATIE</au><au>YAO, YIHONG</au><au>DAVIS, GERARD</au><au>GRANT, ETHAN</au><au>GREENLEES, LYDIA</au><au>CHOWDHURY, PARTHA</au><au>RANADE, KOUSTUBH</au><au>JEANBLANC, NICOLETTE</au><au>LIANG, MEINA</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>NOVEL ASSAY TO DETECT HUMAN PERIOSTIN</title><date>2015-08-13</date><risdate>2015</risdate><abstract>This disclosure provides a robust, sensitive, and specific assay for the detection and measurement of periostin levels in samples obtained from human patients having, or suspected of having an IL-13-mediated disease or disorder. The disclosure further provides novel antiperiostin monoclonal antibodies that recognize at least isoforms 1, 2, 3, 4, 7, and 8 of human periostin, and assay kits comprising one or more of these antibodies.
La présente invention concerne un essai biologique robuste, sensible, et spécifique pour la détection et la mesure de niveaux de la périostine dans des échantillons obtenus à partir de patients humains atteints, ou suspectés d'être atteints par une maladie ou d'un trouble provoqué(e) par l'IL -13. L'invention concerne également de nouveaux anticorps monoclonaux anti-périostine qui reconnaissent au moins des isoformes 1, 2, 3, 4, 7 et 8 de la périostine humaine, et des trousses d'essai biologique comportant un ou plusieurs de ces anticorps.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING METALLURGY ORGANIC CHEMISTRY PEPTIDES PHYSICS TESTING |
| title | NOVEL ASSAY TO DETECT HUMAN PERIOSTIN |
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