ENHANCED PROTEIN EXPRESSION
The present invention relates in general to bacterial cells having a genetic alteration that results in increased expression of a protein of interest and methods of making and using such cells. Aspects of the present invention include Gram positive microorganisms, such as Bacillus species, having a...
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| creator | OTSUKA, REI VAN KIMMENADE, ANITA BONGIORNI, CRISTINA SCHMIDT, BRIAN F |
| description | The present invention relates in general to bacterial cells having a genetic alteration that results in increased expression of a protein of interest and methods of making and using such cells. Aspects of the present invention include Gram positive microorganisms, such as Bacillus species, having a genetic alteration that modifies activity of a protein encoded by the ykf operon and results in enhanced expression of a protein of interest.
La présente invention porte en général sur des cellules bactériennes ayant une modification génétique qui conduit à l'expression accrue d'une protéine présentant de l'intérêt et sur des procédés de formation et d'utilisation de telles cellules. Des aspects de la présente invention comprennent des micro-organismes à gram positif, tels que l'espèce Bacillus, ayant une modification génétique qui modifie l'activité d'une protéine codée par l'opéron ykf et conduit à l'expression améliorée d'une protéine présentant de l'intérêt. |
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La présente invention porte en général sur des cellules bactériennes ayant une modification génétique qui conduit à l'expression accrue d'une protéine présentant de l'intérêt et sur des procédés de formation et d'utilisation de telles cellules. Des aspects de la présente invention comprennent des micro-organismes à gram positif, tels que l'espèce Bacillus, ayant une modification génétique qui modifie l'activité d'une protéine codée par l'opéron ykf et conduit à l'expression améliorée d'une protéine présentant de l'intérêt.</description><language>eng ; fre</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; ORGANIC CHEMISTRY ; PEPTIDES ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220621&DB=EPODOC&CC=CA&NR=2935066C$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220621&DB=EPODOC&CC=CA&NR=2935066C$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>OTSUKA, REI</creatorcontrib><creatorcontrib>VAN KIMMENADE, ANITA</creatorcontrib><creatorcontrib>BONGIORNI, CRISTINA</creatorcontrib><creatorcontrib>SCHMIDT, BRIAN F</creatorcontrib><title>ENHANCED PROTEIN EXPRESSION</title><description>The present invention relates in general to bacterial cells having a genetic alteration that results in increased expression of a protein of interest and methods of making and using such cells. Aspects of the present invention include Gram positive microorganisms, such as Bacillus species, having a genetic alteration that modifies activity of a protein encoded by the ykf operon and results in enhanced expression of a protein of interest.
La présente invention porte en général sur des cellules bactériennes ayant une modification génétique qui conduit à l'expression accrue d'une protéine présentant de l'intérêt et sur des procédés de formation et d'utilisation de telles cellules. Des aspects de la présente invention comprennent des micro-organismes à gram positif, tels que l'espèce Bacillus, ayant une modification génétique qui modifie l'activité d'une protéine codée par l'opéron ykf et conduit à l'expression améliorée d'une protéine présentant de l'intérêt.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZJB29fNw9HN2dVEICPIPcfX0U3CNCAhyDQ729PfjYWBNS8wpTuWF0twM8m6uIc4euqkF-fGpxQWJyal5qSXxzo5GlsamBmZmzsaEVQAA4Q8fzQ</recordid><startdate>20220621</startdate><enddate>20220621</enddate><creator>OTSUKA, REI</creator><creator>VAN KIMMENADE, ANITA</creator><creator>BONGIORNI, CRISTINA</creator><creator>SCHMIDT, BRIAN F</creator><scope>EVB</scope></search><sort><creationdate>20220621</creationdate><title>ENHANCED PROTEIN EXPRESSION</title><author>OTSUKA, REI ; VAN KIMMENADE, ANITA ; BONGIORNI, CRISTINA ; SCHMIDT, BRIAN F</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CA2935066C3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2022</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>OTSUKA, REI</creatorcontrib><creatorcontrib>VAN KIMMENADE, ANITA</creatorcontrib><creatorcontrib>BONGIORNI, CRISTINA</creatorcontrib><creatorcontrib>SCHMIDT, BRIAN F</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>OTSUKA, REI</au><au>VAN KIMMENADE, ANITA</au><au>BONGIORNI, CRISTINA</au><au>SCHMIDT, BRIAN F</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>ENHANCED PROTEIN EXPRESSION</title><date>2022-06-21</date><risdate>2022</risdate><abstract>The present invention relates in general to bacterial cells having a genetic alteration that results in increased expression of a protein of interest and methods of making and using such cells. Aspects of the present invention include Gram positive microorganisms, such as Bacillus species, having a genetic alteration that modifies activity of a protein encoded by the ykf operon and results in enhanced expression of a protein of interest.
La présente invention porte en général sur des cellules bactériennes ayant une modification génétique qui conduit à l'expression accrue d'une protéine présentant de l'intérêt et sur des procédés de formation et d'utilisation de telles cellules. Des aspects de la présente invention comprennent des micro-organismes à gram positif, tels que l'espèce Bacillus, ayant une modification génétique qui modifie l'activité d'une protéine codée par l'opéron ykf et conduit à l'expression améliorée d'une protéine présentant de l'intérêt.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
| title | ENHANCED PROTEIN EXPRESSION |
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