PHARMACEUTICAL COMPOSITION CONTAINING NITISINONE, AND ITS USE

Disclosed are oral pharmaceutical compositions consisting of nitisinone, lactose, and glyceryl dibehenate, and their use in the treatment of tyrosinemia, such as Hereditary Tyrosinemia type-1 (HT-1), or alkaptonuria. L'invention concerne des compositions pharmaceutiques orales comprenant de la...

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Hauptverfasser: BROWN, TOBIAS JOSEF, FULLER, STEPHEN, HARRISON, JAMES
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creator BROWN, TOBIAS JOSEF
FULLER, STEPHEN
HARRISON, JAMES
description Disclosed are oral pharmaceutical compositions consisting of nitisinone, lactose, and glyceryl dibehenate, and their use in the treatment of tyrosinemia, such as Hereditary Tyrosinemia type-1 (HT-1), or alkaptonuria. L'invention concerne des compositions pharmaceutiques orales comprenant de la nitisinone ou un sel pharmaceutiquement acceptable de celle-ci. Elle concerne leur utilisation dans le traitement de la tyrosinémie, telle que la tyrosinémie héréditaire de type 1 (HT-1) ou l'alcaptonurie. Les compositions de l'invention présentent des caractéristiques de stabilité améliorées. L'invention concerne également des procédés de production de nitisinone.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title PHARMACEUTICAL COMPOSITION CONTAINING NITISINONE, AND ITS USE
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