ISOCHROMENE DERIVATIVES AS PHOSPHOINOSITIDE 3-KINASES INHIBITORS

The invention relates to compounds inhibiting phosphoinositide 3 -kinases (PI3K) of formula (I), and to pharmaceutical compositions comprising them and therapeutic use thereof in the treatment of disorders associated with PI3K enzymes. R(p), Ri, R2, R3, R4, R5, Z, Cy, m and n represent various diffe...

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Bibliographische Detailangaben
Hauptverfasser: CARZANIGA, LAURA, ACCETTA, ALESSANDRO, CAPELLI, ANNA MARIA, BIAGETTI, MATTEO
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The invention relates to compounds inhibiting phosphoinositide 3 -kinases (PI3K) of formula (I), and to pharmaceutical compositions comprising them and therapeutic use thereof in the treatment of disorders associated with PI3K enzymes. R(p), Ri, R2, R3, R4, R5, Z, Cy, m and n represent various different possibilities. La présente invention concerne des composés qui inhibent les phosphoinositide 3-kinases (PI3K), des compositions pharmaceutiques comprenant ces composés et l'utilisation thérapeutique de celles-ci dans le traitement des maladies associées aux enzymes PI3K.