3,4-DIHYDROISOQUINOLIN-2(1H)-YL COMPOUNDS

The invention provides certain 3,4-dihydroisoquinolin-2(1H)-yl compounds, particularly compounds of formula (I), and pharmaceutical compositions thereof. The invention further provides methods of using a compound of formula (I) to treat cognitive impairment associated with Parkinson's disease o...

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Hauptverfasser: HAO, JUNLIANG, SCHAUS, JOHN MEHNERT, BEADLE, CHRISTOPHER DAVID, WOLFANGEL, CRAIG DANIEL, KRUSHINSKI, JOSEPH HERMAN, JR, COATES, DAVID ANDREW, REINHARD, MATTHEW ROBERT
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creator HAO, JUNLIANG
SCHAUS, JOHN MEHNERT
BEADLE, CHRISTOPHER DAVID
WOLFANGEL, CRAIG DANIEL
KRUSHINSKI, JOSEPH HERMAN, JR
COATES, DAVID ANDREW
REINHARD, MATTHEW ROBERT
description The invention provides certain 3,4-dihydroisoquinolin-2(1H)-yl compounds, particularly compounds of formula (I), and pharmaceutical compositions thereof. The invention further provides methods of using a compound of formula (I) to treat cognitive impairment associated with Parkinson's disease or schizophrenia. L'invention concerne certains composés de 3,4-dihydroisoquinoléin-2(1H)-yle, notamment des composés de formule (I), et des compositions pharmaceutiques correspondantes. L'invention concerne en outre des procédés d'utilisation d'un composé de formule (I) pour traiter la déficience cognitive associée à la maladie de Parkinson ou à la schizophrénie.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title 3,4-DIHYDROISOQUINOLIN-2(1H)-YL COMPOUNDS
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