PURIFICATION OF POLYSACCHARIDE PROTEIN CONJUGATES

PURIFICATION OF POLYSACCHARIDE PROTEIN CONJUGATES

The invention describes a method of purifying polysaccharide protein conjugates using mixed mode chromatography. The method involves contacting a crude polysaccharide protein conjugate with a mixed mode resin comprising an inert porous shell and an activated core under conditions of low conductivity...

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Hauptverfasser: MAILA, RAGHAVENDRA, DAMOTHARAN, VIJAYARANGAM, NETTEM, SANDEEP KUMAR
Format: Patent
Sprache:eng ; fre
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CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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creator MAILA, RAGHAVENDRA
DAMOTHARAN, VIJAYARANGAM
NETTEM, SANDEEP KUMAR
description The invention describes a method of purifying polysaccharide protein conjugates using mixed mode chromatography. The method involves contacting a crude polysaccharide protein conjugate with a mixed mode resin comprising an inert porous shell and an activated core under conditions of low conductivity that allow binding of the contaminants and collecting the unbound polysaccharide protein conjugate in a flowthrough.
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subjects CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
title PURIFICATION OF POLYSACCHARIDE PROTEIN CONJUGATES
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