USE OF MICROPARTICLES AND ENDOTHELIAL CELLS WITH DECELLULARIZED ORGANS AND TISSUES
The invention provides a method for maintaining capillary lumen diameter, reducing a decrease in capillary vessel lumen diameter or expanding capillary vessel lumen diameter in a re-endothelialised but otherwise decellularised organ or tissue graft with an intact extracellular matrix (ECM) vascular...
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| creator | SEETAPUN, DOMINIQUE ROSS, JEFFREY |
| description | The invention provides a method for maintaining capillary lumen diameter, reducing a decrease in capillary vessel lumen diameter or expanding capillary vessel lumen diameter in a re-endothelialised but otherwise decellularised organ or tissue graft with an intact extracellular matrix (ECM) vascular network. The method is based on administration of endothelial cells and microparticles to the decellularised ECM.
La présente invention concerne un procédé destiné à conserver le diamètre de la lumière capillaire, à réduire une diminution du diamètre de la lumière des vaisseaux capillaires ou à augmenter le diamètre de la lumière des vaisseaux capillaires dans un organe ou une greffe tissulaire ré-endothélialisé mais cependant décellularisé avec un réseau vasculaire de matrice extracellulaire (ECM) intact. Le procédé repose sur l'administration de cellules endothéliales et de microparticules à la matrice ECM décellularisée. |
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La présente invention concerne un procédé destiné à conserver le diamètre de la lumière capillaire, à réduire une diminution du diamètre de la lumière des vaisseaux capillaires ou à augmenter le diamètre de la lumière des vaisseaux capillaires dans un organe ou une greffe tissulaire ré-endothélialisé mais cependant décellularisé avec un réseau vasculaire de matrice extracellulaire (ECM) intact. Le procédé repose sur l'administration de cellules endothéliales et de microparticules à la matrice ECM décellularisée.</description><language>eng ; fre</language><subject>BEER ; BIOCHEMISTRY ; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR ; ENZYMOLOGY ; HUMAN NECESSITIES ; HYGIENE ; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20221011&DB=EPODOC&CC=CA&NR=2907144C$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,309,781,886,25566,76549</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20221011&DB=EPODOC&CC=CA&NR=2907144C$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>SEETAPUN, DOMINIQUE</creatorcontrib><creatorcontrib>ROSS, JEFFREY</creatorcontrib><title>USE OF MICROPARTICLES AND ENDOTHELIAL CELLS WITH DECELLULARIZED ORGANS AND TISSUES</title><description>The invention provides a method for maintaining capillary lumen diameter, reducing a decrease in capillary vessel lumen diameter or expanding capillary vessel lumen diameter in a re-endothelialised but otherwise decellularised organ or tissue graft with an intact extracellular matrix (ECM) vascular network. The method is based on administration of endothelial cells and microparticles to the decellularised ECM.
La présente invention concerne un procédé destiné à conserver le diamètre de la lumière capillaire, à réduire une diminution du diamètre de la lumière des vaisseaux capillaires ou à augmenter le diamètre de la lumière des vaisseaux capillaires dans un organe ou une greffe tissulaire ré-endothélialisé mais cependant décellularisé avec un réseau vasculaire de matrice extracellulaire (ECM) intact. Le procédé repose sur l'administration de cellules endothéliales et de microparticules à la matrice ECM décellularisée.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>DISINFECTION, STERILISATION, OR DEODORISATION OF AIR</subject><subject>ENZYMOLOGY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZAgKDXZV8HdT8PV0DvIPcAwK8XT2cQ1WcPRzUXD1c_EP8XD18XT0UXB29fEJVgj3DPFQcHEFcUJ9HIM8o1xdFPyD3B39IBpCPIODQ12DeRhY0xJzilN5oTQ3g7yba4izh25qQX58anFBYnJqXmpJvLOjkaWBuaGJibMxYRUAFbkuuQ</recordid><startdate>20221011</startdate><enddate>20221011</enddate><creator>SEETAPUN, DOMINIQUE</creator><creator>ROSS, JEFFREY</creator><scope>EVB</scope></search><sort><creationdate>20221011</creationdate><title>USE OF MICROPARTICLES AND ENDOTHELIAL CELLS WITH DECELLULARIZED ORGANS AND TISSUES</title><author>SEETAPUN, DOMINIQUE ; ROSS, JEFFREY</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CA2907144C3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2022</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>DISINFECTION, STERILISATION, OR DEODORISATION OF AIR</topic><topic>ENZYMOLOGY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>SEETAPUN, DOMINIQUE</creatorcontrib><creatorcontrib>ROSS, JEFFREY</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>SEETAPUN, DOMINIQUE</au><au>ROSS, JEFFREY</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>USE OF MICROPARTICLES AND ENDOTHELIAL CELLS WITH DECELLULARIZED ORGANS AND TISSUES</title><date>2022-10-11</date><risdate>2022</risdate><abstract>The invention provides a method for maintaining capillary lumen diameter, reducing a decrease in capillary vessel lumen diameter or expanding capillary vessel lumen diameter in a re-endothelialised but otherwise decellularised organ or tissue graft with an intact extracellular matrix (ECM) vascular network. The method is based on administration of endothelial cells and microparticles to the decellularised ECM.
La présente invention concerne un procédé destiné à conserver le diamètre de la lumière capillaire, à réduire une diminution du diamètre de la lumière des vaisseaux capillaires ou à augmenter le diamètre de la lumière des vaisseaux capillaires dans un organe ou une greffe tissulaire ré-endothélialisé mais cependant décellularisé avec un réseau vasculaire de matrice extracellulaire (ECM) intact. Le procédé repose sur l'administration de cellules endothéliales et de microparticules à la matrice ECM décellularisée.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA DISINFECTION, STERILISATION, OR DEODORISATION OF AIR ENZYMOLOGY HUMAN NECESSITIES HYGIENE MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METALLURGY METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
| title | USE OF MICROPARTICLES AND ENDOTHELIAL CELLS WITH DECELLULARIZED ORGANS AND TISSUES |
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