PYRAZOLO COMPOUNDS AND USES THEREOF

Provided are compounds useful as inhibitors of one or more histone demethylses, such as KDM5. The invention also provides pharmaceutically acceptable compositions comprising compounds of the present invention and methods of using the present composition in the treatment of various disorders.

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Hauptverfasser: BELLON, STEVEN F, GEHLING, VICTOR S, ORTWINE, DAN, ZHANG, BIRONG, ALBRECHT, BRIAN K, DRAGOVICH, PETER, LIANG, JUN, HARMANGE, JEANRISTOPHE, LAI, TOMMY, LABADIE, SHARADA, KIEFER, JIM
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creator BELLON, STEVEN F
GEHLING, VICTOR S
ORTWINE, DAN
ZHANG, BIRONG
ALBRECHT, BRIAN K
DRAGOVICH, PETER
LIANG, JUN
HARMANGE, JEANRISTOPHE
LAI, TOMMY
LABADIE, SHARADA
KIEFER, JIM
description Provided are compounds useful as inhibitors of one or more histone demethylses, such as KDM5. The invention also provides pharmaceutically acceptable compositions comprising compounds of the present invention and methods of using the present composition in the treatment of various disorders.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title PYRAZOLO COMPOUNDS AND USES THEREOF
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