PDE3/PDE4 INHIBITOR/MUSCARINIC RECEPTOR ANTAGONIST COMBINATION
The invention provides a composition which comprises (a) a PDE3/PDE4 inhibitor which is 9,10-Dimethoxy-2-(2,4,6-trimethylphenylimino)-3-(N-carbamoyl-2-aminoethyl)-3,4,6,7- tetrahydro-2H-pyrimido[6,1-a]isoquinolin-4-one or a pharmaceutically acceptable acid addition salt thereof and (b) a muscarinic...
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| creator | WALKER, MICHAEL J.A CALZETTA, LUIGINO CAZZOLA, MARIO |
| description | The invention provides a composition which comprises (a) a PDE3/PDE4 inhibitor which is 9,10-Dimethoxy-2-(2,4,6-trimethylphenylimino)-3-(N-carbamoyl-2-aminoethyl)-3,4,6,7- tetrahydro-2H-pyrimido[6,1-a]isoquinolin-4-one or a pharmaceutically acceptable acid addition salt thereof and (b) a muscarinic receptor antagonist.
L'invention porte sur une composition qui comprend (a) un inhibiteur de PDE3/PDE4 qui est la 9,10-diméthoxy-2-(2,4,6-triméthylphénylimino)-3-(N-carbamoyl-2-aminoéthyl)-3,4,6,7-tétrahydro-2H-pyrimido[6,1-a]isoquinol-4-one ou un sel d'addition d'acide pharmaceutiquement acceptable de celle-ci et (b) un antagoniste des récepteurs muscariniques. |
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L'invention porte sur une composition qui comprend (a) un inhibiteur de PDE3/PDE4 qui est la 9,10-diméthoxy-2-(2,4,6-triméthylphénylimino)-3-(N-carbamoyl-2-aminoéthyl)-3,4,6,7-tétrahydro-2H-pyrimido[6,1-a]isoquinol-4-one ou un sel d'addition d'acide pharmaceutiquement acceptable de celle-ci et (b) un antagoniste des récepteurs muscariniques.</description><language>eng ; fre</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2021</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210601&DB=EPODOC&CC=CA&NR=2902403C$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76318</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210601&DB=EPODOC&CC=CA&NR=2902403C$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>WALKER, MICHAEL J.A</creatorcontrib><creatorcontrib>CALZETTA, LUIGINO</creatorcontrib><creatorcontrib>CAZZOLA, MARIO</creatorcontrib><title>PDE3/PDE4 INHIBITOR/MUSCARINIC RECEPTOR ANTAGONIST COMBINATION</title><description>The invention provides a composition which comprises (a) a PDE3/PDE4 inhibitor which is 9,10-Dimethoxy-2-(2,4,6-trimethylphenylimino)-3-(N-carbamoyl-2-aminoethyl)-3,4,6,7- tetrahydro-2H-pyrimido[6,1-a]isoquinolin-4-one or a pharmaceutically acceptable acid addition salt thereof and (b) a muscarinic receptor antagonist.
L'invention porte sur une composition qui comprend (a) un inhibiteur de PDE3/PDE4 qui est la 9,10-diméthoxy-2-(2,4,6-triméthylphénylimino)-3-(N-carbamoyl-2-aminoéthyl)-3,4,6,7-tétrahydro-2H-pyrimido[6,1-a]isoquinol-4-one ou un sel d'addition d'acide pharmaceutiquement acceptable de celle-ci et (b) un antagoniste des récepteurs muscariniques.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2021</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLALcHE11gcSJgqefh6eTp4h_kH6vqHBzo5Bnn6ezgpBrs6uAUAxBUe_EEd3fz_P4BAFZ39fJ08_xxBPfz8eBta0xJziVF4ozc0g7-Ya4uyhm1qQH59aXJCYnJqXWhLv7GhkaWBkYmDsbExYBQC7SClP</recordid><startdate>20210601</startdate><enddate>20210601</enddate><creator>WALKER, MICHAEL J.A</creator><creator>CALZETTA, LUIGINO</creator><creator>CAZZOLA, MARIO</creator><scope>EVB</scope></search><sort><creationdate>20210601</creationdate><title>PDE3/PDE4 INHIBITOR/MUSCARINIC RECEPTOR ANTAGONIST COMBINATION</title><author>WALKER, MICHAEL J.A ; CALZETTA, LUIGINO ; CAZZOLA, MARIO</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CA2902403C3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2021</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>WALKER, MICHAEL J.A</creatorcontrib><creatorcontrib>CALZETTA, LUIGINO</creatorcontrib><creatorcontrib>CAZZOLA, MARIO</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>WALKER, MICHAEL J.A</au><au>CALZETTA, LUIGINO</au><au>CAZZOLA, MARIO</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PDE3/PDE4 INHIBITOR/MUSCARINIC RECEPTOR ANTAGONIST COMBINATION</title><date>2021-06-01</date><risdate>2021</risdate><abstract>The invention provides a composition which comprises (a) a PDE3/PDE4 inhibitor which is 9,10-Dimethoxy-2-(2,4,6-trimethylphenylimino)-3-(N-carbamoyl-2-aminoethyl)-3,4,6,7- tetrahydro-2H-pyrimido[6,1-a]isoquinolin-4-one or a pharmaceutically acceptable acid addition salt thereof and (b) a muscarinic receptor antagonist.
L'invention porte sur une composition qui comprend (a) un inhibiteur de PDE3/PDE4 qui est la 9,10-diméthoxy-2-(2,4,6-triméthylphénylimino)-3-(N-carbamoyl-2-aminoéthyl)-3,4,6,7-tétrahydro-2H-pyrimido[6,1-a]isoquinol-4-one ou un sel d'addition d'acide pharmaceutiquement acceptable de celle-ci et (b) un antagoniste des récepteurs muscariniques.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | PDE3/PDE4 INHIBITOR/MUSCARINIC RECEPTOR ANTAGONIST COMBINATION |
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