AZAQUINAZOLINE CARBOXAMIDE DERIVATIVES

Disclosed are azaquinazoline carboxamide derivatives of formula (I) their manufacture and use. Certain examples of such compounds are p70S6K inhibitors, and can be employed, inter alia, for the treatment of hyperproliferative and other disorders. L'invention concerne des nouveaux dérivés carbox...

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Hauptverfasser:	CRONIN, MARK W, NEAGU, CONSTANTIN, BOIVIN, ROCH, GOUTOPOULOS, ANDREAS, POTNICK, JUSTIN, CHEN, XIAOLING, JOHNSON, THERESA L, HUCK, BAYARD R, LAN, RUOXI, DESELM, LIZBETH CELESTE
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Disclosed are azaquinazoline carboxamide derivatives of formula (I) their manufacture and use. Certain examples of such compounds are p70S6K inhibitors, and can be employed, inter alia, for the treatment of hyperproliferative and other disorders. L'invention concerne des nouveaux dérivés carboxamide d'azaquinazoline de formule (I) dans laquelle W1, W2, W3, W4, R1, R2, R3 et m ont la signification indiquée dans la description, sont des inhibiteurs de p70S6K, et peuvent être utilisés, entre autres, pour le traitement de troubles hyperprolifératifs.