METHOD FOR DETECTING CANCER

The present invention provides: a cancer detection method that includes measuring, in a biological sample and using an antigen-antibody reaction, the expression of a polypeptide that has binding reactivity with an antibody against CAPRIN-1 having an amino acid sequence represented by any of the even...

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Hauptverfasser: OKANO, FUMIYOSHI, IDO, TAKAYOSHI
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IDO, TAKAYOSHI
description The present invention provides: a cancer detection method that includes measuring, in a biological sample and using an antigen-antibody reaction, the expression of a polypeptide that has binding reactivity with an antibody against CAPRIN-1 having an amino acid sequence represented by any of the even sequence numbers from SEQ ID NO:2-30 in the sequence listing; a cancer detection method for determining the presence of CAPRIN-1 and the amount thereof in a cancer patient sample, in order to determine the administration, to the cancer patient, of a drug that targets CAPRIN-1; and a cancer diagnostic agent or a cancer diagnostic kit containing an anti-CAPRIN-1 antibody. La présente invention concerne : un procédé de détection de cancer comprenant la mesure, dans un échantillon biologique et l'utilisation d'une réaction antigène-anticorps, de l'expression d'un polypeptide possédant une réactivité de liaison avec un anticorps dirigé contre la CAPRINE-1 comprenant une séquence d'acides aminés représenté par une séquence quelconque parmi des séquences de nombre pair parmi SEQ ID NO:2-30 dans le listage de séquences; un procédé de détection de cancer pour la détermination de la présence de la protéine CAPRINE-1 et la quantité de celle-ci dans un échantillon d'un patient atteint de cancer, afin de déterminer l'administration, au patient atteint de cancer, de traitement thérapeutique qui cible la protéine CAPRINE-1; et un agent de diagnostic de cancer ou une trousse contenant un anticorps anti-protéine CAPRINE-1.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
TESTING
VINEGAR
WINE
title METHOD FOR DETECTING CANCER
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