PYRIDONE DERIVATIVES

Compounds or salts thereof, or crystals thereof, are provided which inhibit Axl and are useful for treating diseases caused by Axl hyperfunction, diseases associated with Axl hyperfunction and/or diseases accompanied by Axl hyperfunction. Pyridone derivatives represented by formula (1) having variou...

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Hauptverfasser: TOMINAGA, YUICHI, SHIBATA, YOSHIHIRO, KOBAYASHI, KATSUHIRO, KOBAYASHI, KEIJIRO, TAKEUCHI, KOSUKE, JIMBO, TAKESHI, OTA, MASAHIRO, WATANABE, HIDEAKI, OHKI, HITOSHI, YAMAGUCHI, AKITAKE, FUKATSU, DAISUKE
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creator TOMINAGA, YUICHI
SHIBATA, YOSHIHIRO
KOBAYASHI, KATSUHIRO
KOBAYASHI, KEIJIRO
TAKEUCHI, KOSUKE
JIMBO, TAKESHI
OTA, MASAHIRO
WATANABE, HIDEAKI
OHKI, HITOSHI
YAMAGUCHI, AKITAKE
FUKATSU, DAISUKE
description Compounds or salts thereof, or crystals thereof, are provided which inhibit Axl and are useful for treating diseases caused by Axl hyperfunction, diseases associated with Axl hyperfunction and/or diseases accompanied by Axl hyperfunction. Pyridone derivatives represented by formula (1) having various substituents or salts thereof, or crystals thereof (where R1, R2, R3, R5, R6, A, W, X and n in the formula (1) are as defined in the specification, respectively) are provided. L'invention concerne : un nouveau composé qui inhibe Axl et est utile dans le traitement de maladies provoquées par une hyperfonction d'Axl, le traitement de maladies apparentées à l'hyperfonction d'Axl, et/ou le traitement de maladies associées à l'hyperfonction d'Ax1 ; un sel de celui-ci ; ou des cristaux de ceux-ci. L'invention concerne un dérivé de pyridone représenté par la formule (1) comportant divers substituants, un sel de celui-ci ou des cristaux de ceux-ci (ici R1, R2, R3, R5, R6, A, W, X et n dans la formule (1) sont chacun tels que définis dans la description).
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Pyridone derivatives represented by formula (1) having various substituents or salts thereof, or crystals thereof (where R1, R2, R3, R5, R6, A, W, X and n in the formula (1) are as defined in the specification, respectively) are provided. L'invention concerne : un nouveau composé qui inhibe Axl et est utile dans le traitement de maladies provoquées par une hyperfonction d'Axl, le traitement de maladies apparentées à l'hyperfonction d'Axl, et/ou le traitement de maladies associées à l'hyperfonction d'Ax1 ; un sel de celui-ci ; ou des cristaux de ceux-ci. 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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title PYRIDONE DERIVATIVES
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