PYRIDONE DERIVATIVES
Compounds or salts thereof, or crystals thereof, are provided which inhibit Axl and are useful for treating diseases caused by Axl hyperfunction, diseases associated with Axl hyperfunction and/or diseases accompanied by Axl hyperfunction. Pyridone derivatives represented by formula (1) having variou...
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creator | TOMINAGA, YUICHI SHIBATA, YOSHIHIRO KOBAYASHI, KATSUHIRO KOBAYASHI, KEIJIRO TAKEUCHI, KOSUKE JIMBO, TAKESHI OTA, MASAHIRO WATANABE, HIDEAKI OHKI, HITOSHI YAMAGUCHI, AKITAKE FUKATSU, DAISUKE |
description | Compounds or salts thereof, or crystals thereof, are provided which inhibit Axl and are useful for treating diseases caused by Axl hyperfunction, diseases associated with Axl hyperfunction and/or diseases accompanied by Axl hyperfunction. Pyridone derivatives represented by formula (1) having various substituents or salts thereof, or crystals thereof (where R1, R2, R3, R5, R6, A, W, X and n in the formula (1) are as defined in the specification, respectively) are provided.
L'invention concerne : un nouveau composé qui inhibe Axl et est utile dans le traitement de maladies provoquées par une hyperfonction d'Axl, le traitement de maladies apparentées à l'hyperfonction d'Axl, et/ou le traitement de maladies associées à l'hyperfonction d'Ax1 ; un sel de celui-ci ; ou des cristaux de ceux-ci. L'invention concerne un dérivé de pyridone représenté par la formule (1) comportant divers substituants, un sel de celui-ci ou des cristaux de ceux-ci (ici R1, R2, R3, R5, R6, A, W, X et n dans la formule (1) sont chacun tels que définis dans la description). |
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L'invention concerne : un nouveau composé qui inhibe Axl et est utile dans le traitement de maladies provoquées par une hyperfonction d'Axl, le traitement de maladies apparentées à l'hyperfonction d'Axl, et/ou le traitement de maladies associées à l'hyperfonction d'Ax1 ; un sel de celui-ci ; ou des cristaux de ceux-ci. L'invention concerne un dérivé de pyridone représenté par la formule (1) comportant divers substituants, un sel de celui-ci ou des cristaux de ceux-ci (ici R1, R2, R3, R5, R6, A, W, X et n dans la formule (1) sont chacun tels que définis dans la description).</description><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2018</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180227&DB=EPODOC&CC=CA&NR=2863515C$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180227&DB=EPODOC&CC=CA&NR=2863515C$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>TOMINAGA, YUICHI</creatorcontrib><creatorcontrib>SHIBATA, YOSHIHIRO</creatorcontrib><creatorcontrib>KOBAYASHI, KATSUHIRO</creatorcontrib><creatorcontrib>KOBAYASHI, KEIJIRO</creatorcontrib><creatorcontrib>TAKEUCHI, KOSUKE</creatorcontrib><creatorcontrib>JIMBO, TAKESHI</creatorcontrib><creatorcontrib>OTA, MASAHIRO</creatorcontrib><creatorcontrib>WATANABE, HIDEAKI</creatorcontrib><creatorcontrib>OHKI, HITOSHI</creatorcontrib><creatorcontrib>YAMAGUCHI, AKITAKE</creatorcontrib><creatorcontrib>FUKATSU, DAISUKE</creatorcontrib><title>PYRIDONE DERIVATIVES</title><description>Compounds or salts thereof, or crystals thereof, are provided which inhibit Axl and are useful for treating diseases caused by Axl hyperfunction, diseases associated with Axl hyperfunction and/or diseases accompanied by Axl hyperfunction. Pyridone derivatives represented by formula (1) having various substituents or salts thereof, or crystals thereof (where R1, R2, R3, R5, R6, A, W, X and n in the formula (1) are as defined in the specification, respectively) are provided.
L'invention concerne : un nouveau composé qui inhibe Axl et est utile dans le traitement de maladies provoquées par une hyperfonction d'Axl, le traitement de maladies apparentées à l'hyperfonction d'Axl, et/ou le traitement de maladies associées à l'hyperfonction d'Ax1 ; un sel de celui-ci ; ou des cristaux de ceux-ci. L'invention concerne un dérivé de pyridone représenté par la formule (1) comportant divers substituants, un sel de celui-ci ou des cristaux de ceux-ci (ici R1, R2, R3, R5, R6, A, W, X et n dans la formule (1) sont chacun tels que définis dans la description).</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2018</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZBAJiAzydPH3c1VwcQ3yDHMM8QxzDeZhYE1LzClO5YXS3Azybq4hzh66qQX58anFBYnJqXmpJfHOjkYWZsamhqbOxoRVAAAWuR3t</recordid><startdate>20180227</startdate><enddate>20180227</enddate><creator>TOMINAGA, YUICHI</creator><creator>SHIBATA, YOSHIHIRO</creator><creator>KOBAYASHI, KATSUHIRO</creator><creator>KOBAYASHI, KEIJIRO</creator><creator>TAKEUCHI, KOSUKE</creator><creator>JIMBO, TAKESHI</creator><creator>OTA, MASAHIRO</creator><creator>WATANABE, HIDEAKI</creator><creator>OHKI, HITOSHI</creator><creator>YAMAGUCHI, AKITAKE</creator><creator>FUKATSU, DAISUKE</creator><scope>EVB</scope></search><sort><creationdate>20180227</creationdate><title>PYRIDONE DERIVATIVES</title><author>TOMINAGA, YUICHI ; SHIBATA, YOSHIHIRO ; KOBAYASHI, KATSUHIRO ; KOBAYASHI, KEIJIRO ; TAKEUCHI, KOSUKE ; JIMBO, TAKESHI ; OTA, MASAHIRO ; WATANABE, HIDEAKI ; OHKI, HITOSHI ; YAMAGUCHI, AKITAKE ; FUKATSU, DAISUKE</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CA2863515C3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2018</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>TOMINAGA, YUICHI</creatorcontrib><creatorcontrib>SHIBATA, YOSHIHIRO</creatorcontrib><creatorcontrib>KOBAYASHI, KATSUHIRO</creatorcontrib><creatorcontrib>KOBAYASHI, KEIJIRO</creatorcontrib><creatorcontrib>TAKEUCHI, KOSUKE</creatorcontrib><creatorcontrib>JIMBO, TAKESHI</creatorcontrib><creatorcontrib>OTA, MASAHIRO</creatorcontrib><creatorcontrib>WATANABE, HIDEAKI</creatorcontrib><creatorcontrib>OHKI, HITOSHI</creatorcontrib><creatorcontrib>YAMAGUCHI, AKITAKE</creatorcontrib><creatorcontrib>FUKATSU, DAISUKE</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>TOMINAGA, YUICHI</au><au>SHIBATA, YOSHIHIRO</au><au>KOBAYASHI, KATSUHIRO</au><au>KOBAYASHI, KEIJIRO</au><au>TAKEUCHI, KOSUKE</au><au>JIMBO, TAKESHI</au><au>OTA, MASAHIRO</au><au>WATANABE, HIDEAKI</au><au>OHKI, HITOSHI</au><au>YAMAGUCHI, AKITAKE</au><au>FUKATSU, DAISUKE</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PYRIDONE DERIVATIVES</title><date>2018-02-27</date><risdate>2018</risdate><abstract>Compounds or salts thereof, or crystals thereof, are provided which inhibit Axl and are useful for treating diseases caused by Axl hyperfunction, diseases associated with Axl hyperfunction and/or diseases accompanied by Axl hyperfunction. Pyridone derivatives represented by formula (1) having various substituents or salts thereof, or crystals thereof (where R1, R2, R3, R5, R6, A, W, X and n in the formula (1) are as defined in the specification, respectively) are provided.
L'invention concerne : un nouveau composé qui inhibe Axl et est utile dans le traitement de maladies provoquées par une hyperfonction d'Axl, le traitement de maladies apparentées à l'hyperfonction d'Axl, et/ou le traitement de maladies associées à l'hyperfonction d'Ax1 ; un sel de celui-ci ; ou des cristaux de ceux-ci. L'invention concerne un dérivé de pyridone représenté par la formule (1) comportant divers substituants, un sel de celui-ci ou des cristaux de ceux-ci (ici R1, R2, R3, R5, R6, A, W, X et n dans la formule (1) sont chacun tels que définis dans la description).</abstract><oa>free_for_read</oa></addata></record> |
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subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | PYRIDONE DERIVATIVES |
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