DPP-4 INHIBITOR
A DPP-4 inhibitor containing, as an active ingredient, a peptide represented by formula (1): Xe-Pro/Ala/Hyp-Xa-Xb-Xc-Xd (wherein Xe represents an amino acid residue having an isoelectric point of 5.9-6.3; Pro/Ala/Hyp represents Pro, Ala or Hyp; Xa represents an amino acid residue other than Hyp, Pro...
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| creator | KUSUBATA, MASASHI TAGA, YUKI KOYAMA, YOUICHI HAYASHIDA, OSAMU ATSUZAWA, YUJI HATTORI, SHUNJI |
| description | A DPP-4 inhibitor containing, as an active ingredient, a peptide represented by formula (1): Xe-Pro/Ala/Hyp-Xa-Xb-Xc-Xd (wherein Xe represents an amino acid residue having an isoelectric point of 5.9-6.3; Pro/Ala/Hyp represents Pro, Ala or Hyp; Xa represents an amino acid residue other than Hyp, Pro and Arg or a deletion; Xb represents Gly, Pro or a deletion; Xc represents Pro, Ala or a deletion; and Xd represents an amino acid residue or a deletion). This inhibitor is expected to exert an activity of decreasing a blood glucose level through the potentiation of the activity of an incretin, and therefore can be used as a therapeutic agent for diabetes. In addition, this inhibitor can act on an immune system or the like, and therefore can be used for the treatment of skin diseases or the like. |
| format | Patent |
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This inhibitor is expected to exert an activity of decreasing a blood glucose level through the potentiation of the activity of an incretin, and therefore can be used as a therapeutic agent for diabetes. In addition, this inhibitor can act on an immune system or the like, and therefore can be used for the treatment of skin diseases or the like.</description><language>eng ; fre</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; ORGANIC CHEMISTRY ; PEPTIDES ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2013</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20130510&DB=EPODOC&CC=CA&NR=2854289A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20130510&DB=EPODOC&CC=CA&NR=2854289A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KUSUBATA, MASASHI</creatorcontrib><creatorcontrib>TAGA, YUKI</creatorcontrib><creatorcontrib>KOYAMA, YOUICHI</creatorcontrib><creatorcontrib>HAYASHIDA, OSAMU</creatorcontrib><creatorcontrib>ATSUZAWA, YUJI</creatorcontrib><creatorcontrib>HATTORI, SHUNJI</creatorcontrib><title>DPP-4 INHIBITOR</title><description>A DPP-4 inhibitor containing, as an active ingredient, a peptide represented by formula (1): Xe-Pro/Ala/Hyp-Xa-Xb-Xc-Xd (wherein Xe represents an amino acid residue having an isoelectric point of 5.9-6.3; Pro/Ala/Hyp represents Pro, Ala or Hyp; Xa represents an amino acid residue other than Hyp, Pro and Arg or a deletion; Xb represents Gly, Pro or a deletion; Xc represents Pro, Ala or a deletion; and Xd represents an amino acid residue or a deletion). This inhibitor is expected to exert an activity of decreasing a blood glucose level through the potentiation of the activity of an incretin, and therefore can be used as a therapeutic agent for diabetes. In addition, this inhibitor can act on an immune system or the like, and therefore can be used for the treatment of skin diseases or the like.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2013</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZOB3CQjQNVHw9PPwdPIM8Q_iYWBNS8wpTuWF0twMCm6uIc4euqkF-fGpxQWJyal5qSXxzo5GFqYmRhaWjobGRCgBAJknHJU</recordid><startdate>20130510</startdate><enddate>20130510</enddate><creator>KUSUBATA, MASASHI</creator><creator>TAGA, YUKI</creator><creator>KOYAMA, YOUICHI</creator><creator>HAYASHIDA, OSAMU</creator><creator>ATSUZAWA, YUJI</creator><creator>HATTORI, SHUNJI</creator><scope>EVB</scope></search><sort><creationdate>20130510</creationdate><title>DPP-4 INHIBITOR</title><author>KUSUBATA, MASASHI ; TAGA, YUKI ; KOYAMA, YOUICHI ; HAYASHIDA, OSAMU ; ATSUZAWA, YUJI ; HATTORI, SHUNJI</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CA2854289A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2013</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>KUSUBATA, MASASHI</creatorcontrib><creatorcontrib>TAGA, YUKI</creatorcontrib><creatorcontrib>KOYAMA, YOUICHI</creatorcontrib><creatorcontrib>HAYASHIDA, OSAMU</creatorcontrib><creatorcontrib>ATSUZAWA, YUJI</creatorcontrib><creatorcontrib>HATTORI, SHUNJI</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>KUSUBATA, MASASHI</au><au>TAGA, YUKI</au><au>KOYAMA, YOUICHI</au><au>HAYASHIDA, OSAMU</au><au>ATSUZAWA, YUJI</au><au>HATTORI, SHUNJI</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>DPP-4 INHIBITOR</title><date>2013-05-10</date><risdate>2013</risdate><abstract>A DPP-4 inhibitor containing, as an active ingredient, a peptide represented by formula (1): Xe-Pro/Ala/Hyp-Xa-Xb-Xc-Xd (wherein Xe represents an amino acid residue having an isoelectric point of 5.9-6.3; Pro/Ala/Hyp represents Pro, Ala or Hyp; Xa represents an amino acid residue other than Hyp, Pro and Arg or a deletion; Xb represents Gly, Pro or a deletion; Xc represents Pro, Ala or a deletion; and Xd represents an amino acid residue or a deletion). This inhibitor is expected to exert an activity of decreasing a blood glucose level through the potentiation of the activity of an incretin, and therefore can be used as a therapeutic agent for diabetes. In addition, this inhibitor can act on an immune system or the like, and therefore can be used for the treatment of skin diseases or the like.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
| title | DPP-4 INHIBITOR |
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