TYROSINE BASED LINKERS FOR THE RELEASABLE CONNECTION OF PEPTIDES

The invention relates to novel tyrosine based linkers that allow the releasable connection of peptides or proteins with other molecular entities, e.g. polyethylene glycol, to processes for their preparation and their use for preparing medicaments for the treatment and/or prophylaxis of diseases.

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Hauptverfasser: GRIEBENOW, NILS, FLAMME, INGO, SCHOHE-LOOP, RUDOLF, WITTROCK, SVEN, KRENZ, URSULA, KOBBERLING, JOHANNES, LERCHEN, HANS-GEORG
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creator GRIEBENOW, NILS
FLAMME, INGO
SCHOHE-LOOP, RUDOLF
WITTROCK, SVEN
KRENZ, URSULA
KOBBERLING, JOHANNES
LERCHEN, HANS-GEORG
description The invention relates to novel tyrosine based linkers that allow the releasable connection of peptides or proteins with other molecular entities, e.g. polyethylene glycol, to processes for their preparation and their use for preparing medicaments for the treatment and/or prophylaxis of diseases.
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title TYROSINE BASED LINKERS FOR THE RELEASABLE CONNECTION OF PEPTIDES
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