A SOLID DISPERSION OF N4-(4-([1,2,4]TRIAZOLO[1,5-A]PYRIDIN-7-YLOXY)-3-METHYLPHENYL)-N6-(4,4-DIMETHYL-4,5-DIHYDROOXAZOL-2-YL)QUINAZOLINE-4,6-DIAMINE

A solid dispersion of N4-(4-([1, 2, 4]triazolo[1,5-a]pyridin-7-yloxy)-3-methylphenyl)-N6-(4,4-dimethyl-4,5-dihydrooxazol-2-yl)quinazoline-4,6-diamine and processes for preparing the solid dispersion are provided herein. Also, a pharmaceutical composition comprising a solid dispersion of N4-(4-([1,2,...

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Bibliographische Detailangaben
Hauptverfasser:	DUBOSE, DEVON BREVARD, FRY, DAVID SHANK, GAUTSCHI, JEFF, SMITHEY, DAN, LINDEMANN, CHRISTOPHER M, PREIGH, MICHAEL, CRAIG, CHRISTOPHER DONOVAN, BLOOM, COREY JAY
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	A solid dispersion of N4-(4-([1, 2, 4]triazolo[1,5-a]pyridin-7-yloxy)-3-methylphenyl)-N6-(4,4-dimethyl-4,5-dihydrooxazol-2-yl)quinazoline-4,6-diamine and processes for preparing the solid dispersion are provided herein. Also, a pharmaceutical composition comprising a solid dispersion of N4-(4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)-3- methylphenyl)-N6-(4,4-dimethyl-4,5-dihydrooxazol-2-yl)quinazoline-4,6-diamine and uses thereof are provided herein. La présente invention porte sur une dispersion solide de N4-(4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)-3-méthylphényl)-N6-(4,4-diméthyl-4,5-dihydrooxazol-2-yl)quinazoline-4,6-diamine et sur des procédés de préparation de la dispersion solide. De plus, la présente invention porte sur une composition pharmaceutique comportant une dispersion solide de N4-(4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)-3-méthylphényl)-N6-(4,4-diméthyl-4,5-dihydrooxazol-2-yl)quinazoline-4,6-diamine et sur ses utilisations.