BENZONITRILE DERIVATIVES AS KINASE INHIBITORS
The invention relates to compounds of the formula (I), wherein R1, R2, X and Y have the meaning specified in claim 1, are inhibitors of TBK1 and ???e, and can be used, inter alia, for the treatment of cancer and inflammatory diseases. L'invention concerne des composés de la formule (I), dans la...
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| creator | DORSCH, DIETER EGGENWEILER, HANS-MICHAEL HOELZEMANN, GUENTER |
| description | The invention relates to compounds of the formula (I), wherein R1, R2, X and Y have the meaning specified in claim 1, are inhibitors of TBK1 and ???e, and can be used, inter alia, for the treatment of cancer and inflammatory diseases.
L'invention concerne des composés de la formule (I), dans laquelle R1, R2, X et Y, qui ont les significations données dans la revendication 1, sont des inhibiteurs de TBK1 et IKKe et peuvent être utilisés, entre autres, pour le traitement du cancer et de maladies inflammatoires. |
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L'invention concerne des composés de la formule (I), dans laquelle R1, R2, X et Y, qui ont les significations données dans la revendication 1, sont des inhibiteurs de TBK1 et IKKe et peuvent être utilisés, entre autres, pour le traitement du cancer et de maladies inflammatoires.</description><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2019</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20190604&DB=EPODOC&CC=CA&NR=2848148C$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,309,782,887,25571,76555</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20190604&DB=EPODOC&CC=CA&NR=2848148C$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>DORSCH, DIETER</creatorcontrib><creatorcontrib>EGGENWEILER, HANS-MICHAEL</creatorcontrib><creatorcontrib>HOELZEMANN, GUENTER</creatorcontrib><title>BENZONITRILE DERIVATIVES AS KINASE INHIBITORS</title><description>The invention relates to compounds of the formula (I), wherein R1, R2, X and Y have the meaning specified in claim 1, are inhibitors of TBK1 and ???e, and can be used, inter alia, for the treatment of cancer and inflammatory diseases.
L'invention concerne des composés de la formule (I), dans laquelle R1, R2, X et Y, qui ont les significations données dans la revendication 1, sont des inhibiteurs de TBK1 et IKKe et peuvent être utilisés, entre autres, pour le traitement du cancer et de maladies inflammatoires.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2019</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNB1cvWL8vfzDAny9HFVcHEN8gxzDPEMcw1WcAxW8Pb0cwx2VfD08_B08gzxDwrmYWBNS8wpTuWF0twM8m6uIc4euqkF-fGpxQWJyal5qSXxzo5GFiYWhiYWzsaEVQAATIMk5Q</recordid><startdate>20190604</startdate><enddate>20190604</enddate><creator>DORSCH, DIETER</creator><creator>EGGENWEILER, HANS-MICHAEL</creator><creator>HOELZEMANN, GUENTER</creator><scope>EVB</scope></search><sort><creationdate>20190604</creationdate><title>BENZONITRILE DERIVATIVES AS KINASE INHIBITORS</title><author>DORSCH, DIETER ; EGGENWEILER, HANS-MICHAEL ; HOELZEMANN, GUENTER</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CA2848148C3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2019</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>DORSCH, DIETER</creatorcontrib><creatorcontrib>EGGENWEILER, HANS-MICHAEL</creatorcontrib><creatorcontrib>HOELZEMANN, GUENTER</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>DORSCH, DIETER</au><au>EGGENWEILER, HANS-MICHAEL</au><au>HOELZEMANN, GUENTER</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>BENZONITRILE DERIVATIVES AS KINASE INHIBITORS</title><date>2019-06-04</date><risdate>2019</risdate><abstract>The invention relates to compounds of the formula (I), wherein R1, R2, X and Y have the meaning specified in claim 1, are inhibitors of TBK1 and ???e, and can be used, inter alia, for the treatment of cancer and inflammatory diseases.
L'invention concerne des composés de la formule (I), dans laquelle R1, R2, X et Y, qui ont les significations données dans la revendication 1, sont des inhibiteurs de TBK1 et IKKe et peuvent être utilisés, entre autres, pour le traitement du cancer et de maladies inflammatoires.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | BENZONITRILE DERIVATIVES AS KINASE INHIBITORS |
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