COMPOSITIONS AND METHODS FOR MODULATING FARNESOID X RECEPTORS
The present invention relates to compounds of Formula (I), a stereoisomer, enantiomer, a pharmaceutically acceptable salt or an amino acid conjugate thereof; wherein variables are as defined herein; and their pharmaceutical compositions, which are useful as modulators of the activity of Farnesiod X...
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| creator | RUCKER, PAUL VINCENT ALPER, PHILLIP B MUTNICK, DANIEL CHIANELLI, DONATELLA TULLY, DAVID C |
| description | The present invention relates to compounds of Formula (I), a stereoisomer, enantiomer, a pharmaceutically acceptable salt or an amino acid conjugate thereof; wherein variables are as defined herein; and their pharmaceutical compositions, which are useful as modulators of the activity of Farnesiod X receptors (FXR).
La présente invention concerne des composés de Formule (I), un stéréoisomère, énantiomère, sel pharmaceutiquement acceptable ou son conjugué acide aminé ; les variables étant telles que définies présentement ; et leurs compositions pharmaceutiques qui sont utiles comme modulateurs de l'activité de récepteurs du Farnésoïde X (FXR). |
| format | Patent |
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La présente invention concerne des composés de Formule (I), un stéréoisomère, énantiomère, sel pharmaceutiquement acceptable ou son conjugué acide aminé ; les variables étant telles que définies présentement ; et leurs compositions pharmaceutiques qui sont utiles comme modulateurs de l'activité de récepteurs du Farnésoïde X (FXR).</description><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2019</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20190507&DB=EPODOC&CC=CA&NR=2819825C$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20190507&DB=EPODOC&CC=CA&NR=2819825C$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>RUCKER, PAUL VINCENT</creatorcontrib><creatorcontrib>ALPER, PHILLIP B</creatorcontrib><creatorcontrib>MUTNICK, DANIEL</creatorcontrib><creatorcontrib>CHIANELLI, DONATELLA</creatorcontrib><creatorcontrib>TULLY, DAVID C</creatorcontrib><title>COMPOSITIONS AND METHODS FOR MODULATING FARNESOID X RECEPTORS</title><description>The present invention relates to compounds of Formula (I), a stereoisomer, enantiomer, a pharmaceutically acceptable salt or an amino acid conjugate thereof; wherein variables are as defined herein; and their pharmaceutical compositions, which are useful as modulators of the activity of Farnesiod X receptors (FXR).
La présente invention concerne des composés de Formule (I), un stéréoisomère, énantiomère, sel pharmaceutiquement acceptable ou son conjugué acide aminé ; les variables étant telles que définies présentement ; et leurs compositions pharmaceutiques qui sont utiles comme modulateurs de l'activité de récepteurs du Farnésoïde X (FXR).</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2019</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLB19vcN8A_2DPH09wtWcPRzUfB1DfHwdwlWcPMPUvD1dwn1cQzx9HNXcHMM8nMN9vd0UYhQCHJ1dg0I8Q8K5mFgTUvMKU7lhdLcDPJuriHOHrqpBfnxqcUFicmpeakl8c6ORhaGlhZGps7GhFUAAKz-KUM</recordid><startdate>20190507</startdate><enddate>20190507</enddate><creator>RUCKER, PAUL VINCENT</creator><creator>ALPER, PHILLIP B</creator><creator>MUTNICK, DANIEL</creator><creator>CHIANELLI, DONATELLA</creator><creator>TULLY, DAVID C</creator><scope>EVB</scope></search><sort><creationdate>20190507</creationdate><title>COMPOSITIONS AND METHODS FOR MODULATING FARNESOID X RECEPTORS</title><author>RUCKER, PAUL VINCENT ; ALPER, PHILLIP B ; MUTNICK, DANIEL ; CHIANELLI, DONATELLA ; TULLY, DAVID C</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CA2819825C3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2019</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>RUCKER, PAUL VINCENT</creatorcontrib><creatorcontrib>ALPER, PHILLIP B</creatorcontrib><creatorcontrib>MUTNICK, DANIEL</creatorcontrib><creatorcontrib>CHIANELLI, DONATELLA</creatorcontrib><creatorcontrib>TULLY, DAVID C</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>RUCKER, PAUL VINCENT</au><au>ALPER, PHILLIP B</au><au>MUTNICK, DANIEL</au><au>CHIANELLI, DONATELLA</au><au>TULLY, DAVID C</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>COMPOSITIONS AND METHODS FOR MODULATING FARNESOID X RECEPTORS</title><date>2019-05-07</date><risdate>2019</risdate><abstract>The present invention relates to compounds of Formula (I), a stereoisomer, enantiomer, a pharmaceutically acceptable salt or an amino acid conjugate thereof; wherein variables are as defined herein; and their pharmaceutical compositions, which are useful as modulators of the activity of Farnesiod X receptors (FXR).
La présente invention concerne des composés de Formule (I), un stéréoisomère, énantiomère, sel pharmaceutiquement acceptable ou son conjugué acide aminé ; les variables étant telles que définies présentement ; et leurs compositions pharmaceutiques qui sont utiles comme modulateurs de l'activité de récepteurs du Farnésoïde X (FXR).</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | COMPOSITIONS AND METHODS FOR MODULATING FARNESOID X RECEPTORS |
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