PROCESSES FOR THE PREPARATION OF 3-((PYRROL-2-YL)METHYLENE)-2-PYRROLONES USING 2-SILYLOXY-PYRROLES
The present invention provides for synthetic processes for the making of substituted 3-((pyrrol-2-yl)methylene)-2-pyrrolones, including sunitinib. The present invention also provides for a process of crystallizing substantially pure sunitinib L-malate. La présente invention porte sur des procédés de...
Gespeichert in:
| Hauptverfasser: | , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; fre |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | CHEN, YUNG-FA HENSCHKE, JULIAN P |
| description | The present invention provides for synthetic processes for the making of substituted 3-((pyrrol-2-yl)methylene)-2-pyrrolones, including sunitinib. The present invention also provides for a process of crystallizing substantially pure sunitinib L-malate.
La présente invention porte sur des procédés de synthèse pour la fabrication de 3-((pyrrol-2-yl)méthylène)-2-pyrrolones substituées, dont le sunitinib. La présente invention porte également sur un procédé de cristallisation de L-malate de sunitinib pratiquement pur. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_CA2816559C</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>CA2816559C</sourcerecordid><originalsourceid>FETCH-epo_espacenet_CA2816559C3</originalsourceid><addsrcrecordid>eNrjZEgKCPJ3dg0Odg1WcPMPUgjxcFUICHINcAxyDPH091Pwd1Mw1tXQCIgMCvL30TXSjfTR9HUN8Yj0cfVz1QTyIRL-fkDtocGefu4KRrrBnj6RPv4RkVA512AeBta0xJziVF4ozc0g7-Ya4uyhm1qQH59aXJCYnJqXWhLv7GhkYWhmamrpbExYBQAYIjM-</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>PROCESSES FOR THE PREPARATION OF 3-((PYRROL-2-YL)METHYLENE)-2-PYRROLONES USING 2-SILYLOXY-PYRROLES</title><source>esp@cenet</source><creator>CHEN, YUNG-FA ; HENSCHKE, JULIAN P</creator><creatorcontrib>CHEN, YUNG-FA ; HENSCHKE, JULIAN P</creatorcontrib><description>The present invention provides for synthetic processes for the making of substituted 3-((pyrrol-2-yl)methylene)-2-pyrrolones, including sunitinib. The present invention also provides for a process of crystallizing substantially pure sunitinib L-malate.
La présente invention porte sur des procédés de synthèse pour la fabrication de 3-((pyrrol-2-yl)méthylène)-2-pyrrolones substituées, dont le sunitinib. La présente invention porte également sur un procédé de cristallisation de L-malate de sunitinib pratiquement pur.</description><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; METALLURGY ; ORGANIC CHEMISTRY</subject><creationdate>2018</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180213&DB=EPODOC&CC=CA&NR=2816559C$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,778,883,25551,76302</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180213&DB=EPODOC&CC=CA&NR=2816559C$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>CHEN, YUNG-FA</creatorcontrib><creatorcontrib>HENSCHKE, JULIAN P</creatorcontrib><title>PROCESSES FOR THE PREPARATION OF 3-((PYRROL-2-YL)METHYLENE)-2-PYRROLONES USING 2-SILYLOXY-PYRROLES</title><description>The present invention provides for synthetic processes for the making of substituted 3-((pyrrol-2-yl)methylene)-2-pyrrolones, including sunitinib. The present invention also provides for a process of crystallizing substantially pure sunitinib L-malate.
La présente invention porte sur des procédés de synthèse pour la fabrication de 3-((pyrrol-2-yl)méthylène)-2-pyrrolones substituées, dont le sunitinib. La présente invention porte également sur un procédé de cristallisation de L-malate de sunitinib pratiquement pur.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2018</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZEgKCPJ3dg0Odg1WcPMPUgjxcFUICHINcAxyDPH091Pwd1Mw1tXQCIgMCvL30TXSjfTR9HUN8Yj0cfVz1QTyIRL-fkDtocGefu4KRrrBnj6RPv4RkVA512AeBta0xJziVF4ozc0g7-Ya4uyhm1qQH59aXJCYnJqXWhLv7GhkYWhmamrpbExYBQAYIjM-</recordid><startdate>20180213</startdate><enddate>20180213</enddate><creator>CHEN, YUNG-FA</creator><creator>HENSCHKE, JULIAN P</creator><scope>EVB</scope></search><sort><creationdate>20180213</creationdate><title>PROCESSES FOR THE PREPARATION OF 3-((PYRROL-2-YL)METHYLENE)-2-PYRROLONES USING 2-SILYLOXY-PYRROLES</title><author>CHEN, YUNG-FA ; HENSCHKE, JULIAN P</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CA2816559C3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2018</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><toplevel>online_resources</toplevel><creatorcontrib>CHEN, YUNG-FA</creatorcontrib><creatorcontrib>HENSCHKE, JULIAN P</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>CHEN, YUNG-FA</au><au>HENSCHKE, JULIAN P</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PROCESSES FOR THE PREPARATION OF 3-((PYRROL-2-YL)METHYLENE)-2-PYRROLONES USING 2-SILYLOXY-PYRROLES</title><date>2018-02-13</date><risdate>2018</risdate><abstract>The present invention provides for synthetic processes for the making of substituted 3-((pyrrol-2-yl)methylene)-2-pyrrolones, including sunitinib. The present invention also provides for a process of crystallizing substantially pure sunitinib L-malate.
La présente invention porte sur des procédés de synthèse pour la fabrication de 3-((pyrrol-2-yl)méthylène)-2-pyrrolones substituées, dont le sunitinib. La présente invention porte également sur un procédé de cristallisation de L-malate de sunitinib pratiquement pur.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; fre |
| recordid | cdi_epo_espacenet_CA2816559C |
| source | esp@cenet |
| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY |
| title | PROCESSES FOR THE PREPARATION OF 3-((PYRROL-2-YL)METHYLENE)-2-PYRROLONES USING 2-SILYLOXY-PYRROLES |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-15T16%3A28%3A45IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=CHEN,%20YUNG-FA&rft.date=2018-02-13&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3ECA2816559C%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |