GASTRIC RESISTANT PHARMACEUTICAL OR NUTRACEUTICAL FORMULATION COMPRISING ONE OR MORE SALTS OF ALGINIC ACID

GASTRIC RESISTANT PHARMACEUTICAL OR NUTRACEUTICAL FORMULATION COMPRISING ONE OR MORE SALTS OF ALGINIC ACID

The invention relates to a gastric resistant pharmaceutical or nutraceutical composition, comprising a core, comprising a pharmaceutical or nutraceutical active ingredient and a gastric resistant coating layer onto the core, wherein the release of the pharmaceutical or nutraceutical active ingredien...

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Hauptverfasser: GAWDE, SEEMA YASHWANT, BODINGE, SHRADDHA ASHOK, PAGAR, HEMANT KARBHARI, HAKSAR, PRIYANKA BANSILAL, PETEREIT, HANS-ULRICH
Format: Patent
Sprache:eng ; fre
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator GAWDE, SEEMA YASHWANT
BODINGE, SHRADDHA ASHOK
PAGAR, HEMANT KARBHARI
HAKSAR, PRIYANKA BANSILAL
PETEREIT, HANS-ULRICH
description The invention relates to a gastric resistant pharmaceutical or nutraceutical composition, comprising a core, comprising a pharmaceutical or nutraceutical active ingredient and a gastric resistant coating layer onto the core, wherein the release of the pharmaceutical or nutraceutical active ingredient is not more than 15 % under in-vitro conditions at pH 1.2 for 2 hours in medium according to USP with and without the addition of 40 % (v/v) ethanol, wherein the gastric resistant coating layer comprises 10 to 100 % by weight of one or more salts of alginic acid with a viscosity of 30 to 720 cP of a 1 % aqueous solution. La présente invention concerne une composition pharmaceutique ou nutraceutique gastro-résistante, comprenant un cur constitué d'un principe actif pharmaceutique ou nutraceutique et d'une couche d'enrobage du cur gastro-résistante, la libération du principe actif pharmaceutique ou nutraceutique étant au maximum de 15 % en conditions in vitro à pH 1,2 pendant 2 heures dans un milieu conforme aux recommandations de l'USP avec et sans addition de 40 % d'éthanol en volume, la couche d'enrobage gastro-résistante comprenant entre 10 et 100 % en masse d'un ou de plusieurs sels d'acide alginique avec une viscosité d'une solution aqueuse 1 % comprise entre 30 et 720 cP.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title GASTRIC RESISTANT PHARMACEUTICAL OR NUTRACEUTICAL FORMULATION COMPRISING ONE OR MORE SALTS OF ALGINIC ACID
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