SULFONE COMPOUNDS AS 5-HT6 RECEPTOR LIGANDS
The present invention relates to novel sulfone compounds as 5-HT6 receptor ligands of the formula (I), and their derivatives, prodrugs, tautomers, stereoisomers, polymorphs, solvates, hydrates, metabolites, N-oxides, pharmaceutically acceptable salts and compositions containing them. The present inv...
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| creator | MULLA, MOHAMAD SADIK ABDULHAMID BADANGE, RAJESH KUMAR CHINDHE, ANIL KASHINATH JASTI, VENKATESWARLU REBALLI, VEENA NIROGI, RAMAKRISHNA AHMAD, ISHTIYAQUE ABRAHAM, RENNY SHINDE, ANIL KARBHARI KAMBHAMPATI, RAMA SASTRI NAMALA, RAMBABU |
| description | The present invention relates to novel sulfone compounds as 5-HT6 receptor ligands of the formula (I), and their derivatives, prodrugs, tautomers, stereoisomers, polymorphs, solvates, hydrates, metabolites, N-oxides, pharmaceutically acceptable salts and compositions containing them. The present invention also relates to a process for the preparation of above said novel compounds, and their derivatives, prodrugs, tautomers, stereoisomers, polymorphs, solvates, hydrates, metabolites, N-oxides, pharmaceutically acceptable salts and compositions containing them. These compounds are useful in the treatment/prevention of various disorders that are related to 5-HT6 receptor functions.
La présente invention concerne de nouveaux composés sulfones en tant que ligands du récepteur 5-HT6, représentés par la formule (I), et leurs dérivés, promédicaments, tautomères, stéréo-isomères, polymorphes, solvates, hydrates, métabolites, N-oxydes et sels de qualité pharmaceutique, ainsi que des compositions les contenant. La présente invention porte également sur un procédé de préparation desdits nouveaux composés ci-dessus et de leurs dérivés, promédicaments, tautomères, stéréo-isomères, polymorphes, solvates, hydrates, métabolites, N-oxydes et sels de qualité pharmaceutique, ainsi que des compositions les contenant. Ces composés sont utiles dans le traitement/la prévention de divers troubles qui sont liés aux fonctions du récepteur 5-HT6. |
| format | Patent |
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La présente invention concerne de nouveaux composés sulfones en tant que ligands du récepteur 5-HT6, représentés par la formule (I), et leurs dérivés, promédicaments, tautomères, stéréo-isomères, polymorphes, solvates, hydrates, métabolites, N-oxydes et sels de qualité pharmaceutique, ainsi que des compositions les contenant. La présente invention porte également sur un procédé de préparation desdits nouveaux composés ci-dessus et de leurs dérivés, promédicaments, tautomères, stéréo-isomères, polymorphes, solvates, hydrates, métabolites, N-oxydes et sels de qualité pharmaceutique, ainsi que des compositions les contenant. Ces composés sont utiles dans le traitement/la prévention de divers troubles qui sont liés aux fonctions du récepteur 5-HT6.</description><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2014</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20141028&DB=EPODOC&CC=CA&NR=2786072C$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20141028&DB=EPODOC&CC=CA&NR=2786072C$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>MULLA, MOHAMAD SADIK ABDULHAMID</creatorcontrib><creatorcontrib>BADANGE, RAJESH KUMAR</creatorcontrib><creatorcontrib>CHINDHE, ANIL KASHINATH</creatorcontrib><creatorcontrib>JASTI, VENKATESWARLU</creatorcontrib><creatorcontrib>REBALLI, VEENA</creatorcontrib><creatorcontrib>NIROGI, RAMAKRISHNA</creatorcontrib><creatorcontrib>AHMAD, ISHTIYAQUE</creatorcontrib><creatorcontrib>ABRAHAM, RENNY</creatorcontrib><creatorcontrib>SHINDE, ANIL KARBHARI</creatorcontrib><creatorcontrib>KAMBHAMPATI, RAMA SASTRI</creatorcontrib><creatorcontrib>NAMALA, RAMBABU</creatorcontrib><title>SULFONE COMPOUNDS AS 5-HT6 RECEPTOR LIGANDS</title><description>The present invention relates to novel sulfone compounds as 5-HT6 receptor ligands of the formula (I), and their derivatives, prodrugs, tautomers, stereoisomers, polymorphs, solvates, hydrates, metabolites, N-oxides, pharmaceutically acceptable salts and compositions containing them. The present invention also relates to a process for the preparation of above said novel compounds, and their derivatives, prodrugs, tautomers, stereoisomers, polymorphs, solvates, hydrates, metabolites, N-oxides, pharmaceutically acceptable salts and compositions containing them. These compounds are useful in the treatment/prevention of various disorders that are related to 5-HT6 receptor functions.
La présente invention concerne de nouveaux composés sulfones en tant que ligands du récepteur 5-HT6, représentés par la formule (I), et leurs dérivés, promédicaments, tautomères, stéréo-isomères, polymorphes, solvates, hydrates, métabolites, N-oxydes et sels de qualité pharmaceutique, ainsi que des compositions les contenant. La présente invention porte également sur un procédé de préparation desdits nouveaux composés ci-dessus et de leurs dérivés, promédicaments, tautomères, stéréo-isomères, polymorphes, solvates, hydrates, métabolites, N-oxydes et sels de qualité pharmaceutique, ainsi que des compositions les contenant. Ces composés sont utiles dans le traitement/la prévention de divers troubles qui sont liés aux fonctions du récepteur 5-HT6.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2014</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNAODvVx8_dzVXD29w3wD_VzCVZwDFYw1fUIMVMIcnV2DQjxD1Lw8XR3BMrwMLCmJeYUp_JCaW4GeTfXEGcP3dSC_PjU4oLE5NS81JJ4Z0cjcwszA3MjZ2PCKgDTgyPa</recordid><startdate>20141028</startdate><enddate>20141028</enddate><creator>MULLA, MOHAMAD SADIK ABDULHAMID</creator><creator>BADANGE, RAJESH KUMAR</creator><creator>CHINDHE, ANIL KASHINATH</creator><creator>JASTI, VENKATESWARLU</creator><creator>REBALLI, VEENA</creator><creator>NIROGI, RAMAKRISHNA</creator><creator>AHMAD, ISHTIYAQUE</creator><creator>ABRAHAM, RENNY</creator><creator>SHINDE, ANIL KARBHARI</creator><creator>KAMBHAMPATI, RAMA SASTRI</creator><creator>NAMALA, RAMBABU</creator><scope>EVB</scope></search><sort><creationdate>20141028</creationdate><title>SULFONE COMPOUNDS AS 5-HT6 RECEPTOR LIGANDS</title><author>MULLA, MOHAMAD SADIK ABDULHAMID ; BADANGE, RAJESH KUMAR ; CHINDHE, ANIL KASHINATH ; JASTI, VENKATESWARLU ; REBALLI, VEENA ; NIROGI, RAMAKRISHNA ; AHMAD, ISHTIYAQUE ; ABRAHAM, RENNY ; SHINDE, ANIL KARBHARI ; KAMBHAMPATI, RAMA SASTRI ; NAMALA, RAMBABU</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CA2786072C3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2014</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>MULLA, MOHAMAD SADIK ABDULHAMID</creatorcontrib><creatorcontrib>BADANGE, RAJESH KUMAR</creatorcontrib><creatorcontrib>CHINDHE, ANIL KASHINATH</creatorcontrib><creatorcontrib>JASTI, VENKATESWARLU</creatorcontrib><creatorcontrib>REBALLI, VEENA</creatorcontrib><creatorcontrib>NIROGI, RAMAKRISHNA</creatorcontrib><creatorcontrib>AHMAD, ISHTIYAQUE</creatorcontrib><creatorcontrib>ABRAHAM, RENNY</creatorcontrib><creatorcontrib>SHINDE, ANIL KARBHARI</creatorcontrib><creatorcontrib>KAMBHAMPATI, RAMA SASTRI</creatorcontrib><creatorcontrib>NAMALA, RAMBABU</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>MULLA, MOHAMAD SADIK ABDULHAMID</au><au>BADANGE, RAJESH KUMAR</au><au>CHINDHE, ANIL KASHINATH</au><au>JASTI, VENKATESWARLU</au><au>REBALLI, VEENA</au><au>NIROGI, RAMAKRISHNA</au><au>AHMAD, ISHTIYAQUE</au><au>ABRAHAM, RENNY</au><au>SHINDE, ANIL KARBHARI</au><au>KAMBHAMPATI, RAMA SASTRI</au><au>NAMALA, RAMBABU</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>SULFONE COMPOUNDS AS 5-HT6 RECEPTOR LIGANDS</title><date>2014-10-28</date><risdate>2014</risdate><abstract>The present invention relates to novel sulfone compounds as 5-HT6 receptor ligands of the formula (I), and their derivatives, prodrugs, tautomers, stereoisomers, polymorphs, solvates, hydrates, metabolites, N-oxides, pharmaceutically acceptable salts and compositions containing them. The present invention also relates to a process for the preparation of above said novel compounds, and their derivatives, prodrugs, tautomers, stereoisomers, polymorphs, solvates, hydrates, metabolites, N-oxides, pharmaceutically acceptable salts and compositions containing them. These compounds are useful in the treatment/prevention of various disorders that are related to 5-HT6 receptor functions.
La présente invention concerne de nouveaux composés sulfones en tant que ligands du récepteur 5-HT6, représentés par la formule (I), et leurs dérivés, promédicaments, tautomères, stéréo-isomères, polymorphes, solvates, hydrates, métabolites, N-oxydes et sels de qualité pharmaceutique, ainsi que des compositions les contenant. La présente invention porte également sur un procédé de préparation desdits nouveaux composés ci-dessus et de leurs dérivés, promédicaments, tautomères, stéréo-isomères, polymorphes, solvates, hydrates, métabolites, N-oxydes et sels de qualité pharmaceutique, ainsi que des compositions les contenant. Ces composés sont utiles dans le traitement/la prévention de divers troubles qui sont liés aux fonctions du récepteur 5-HT6.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | SULFONE COMPOUNDS AS 5-HT6 RECEPTOR LIGANDS |
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