PREPARATION OF N-MONOFLUOROALKYL TROPANES

The present invention relates to an improved synthesis of N-monofluoroalkyl tropanes using fluoroalkyl iodides or fluoroalkyl sulfonate esters. The invention also provides the use of such method to prepare the non-radioactive tropane intermediate FP-CIT, and its subsequent conversion to the 123I-lab...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	WILLIAMS, LORENZO, KEILEN, GUNNAR, HAUGAN, JARLE ANDRE
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
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