QUINUCLIDINE COMPOUNDS AS ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS

The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds are ligands for the nicotinic 7 receptor and may be useful for the treatment of various disorders of the central nervous system, especially affective and n...

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Hauptverfasser: WANG, NENGHUI, COOK II, JAMES H, OLSON, RICHARD E, ZUSI, F. CHRISTOPHER, IWUAGWU, CHRISTIANA I, MACOR, JOHN E, KING, DALTON, MCDONALD, IVAR M
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creator WANG, NENGHUI
COOK II, JAMES H
OLSON, RICHARD E
ZUSI, F. CHRISTOPHER
IWUAGWU, CHRISTIANA I
MACOR, JOHN E
KING, DALTON
MCDONALD, IVAR M
description The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds are ligands for the nicotinic 7 receptor and may be useful for the treatment of various disorders of the central nervous system, especially affective and neurodegenerative disorders.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title QUINUCLIDINE COMPOUNDS AS ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS
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