PREPARATION OF NALMEFENE HYDROCHLORIDE FROM NALTREXONE

PREPARATION OF NALMEFENE HYDROCHLORIDE FROM NALTREXONE

Method for producing nalmefene hydrochloride from naltrexone, which method is particular well adapted for large-scale industrial application, and has been found to be efficient, to give a high yield and to afford highly pure nalmefene hy-drochloride salt. L'invention porte sur un procédé pour l...

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Bibliographische Detailangaben
Hauptverfasser: DE FAVERI, CARLA, CASARIN, MAURO, BRUSEGAN, MICHELE
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Zusammenfassung:Method for producing nalmefene hydrochloride from naltrexone, which method is particular well adapted for large-scale industrial application, and has been found to be efficient, to give a high yield and to afford highly pure nalmefene hy-drochloride salt. L'invention porte sur un procédé pour la production de chlorhydrate de nalmefene à partir de naltrexone, lequel procédé est particulièrement bien adapté pour une application industrielle à grande échelle et s'est avéré efficace pour donner un rendement de production élevé et pour fournir du sel de type chlorhydrate de nalmefene extrêmement pur.