ACTIVE PHARMACEUTICAL INGREDIENT ADSORBED ON SOLID SUPPORT

ACTIVE PHARMACEUTICAL INGREDIENT ADSORBED ON SOLID SUPPORT

The present invention belongs to the field of pharmaceutical industry and relates to dosage forms comprising active pharmaceutical ingredients (API) such as tadalafil, simvastatin, fenofibrate and lovastatin that are practically insoluble in water, adsorbed on a carrier. Furthermore it relates to an...

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Hauptverfasser: GRAHEK, ROK, BASTARDA, ANDREJ, PIRC, SAMO, JAKLIC, MIHA TOMAZ, KOCEVAR, KLEMEN
Format: Patent
Sprache:eng ; fre
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator GRAHEK, ROK
BASTARDA, ANDREJ
PIRC, SAMO
JAKLIC, MIHA TOMAZ
KOCEVAR, KLEMEN
description The present invention belongs to the field of pharmaceutical industry and relates to dosage forms comprising active pharmaceutical ingredients (API) such as tadalafil, simvastatin, fenofibrate and lovastatin that are practically insoluble in water, adsorbed on a carrier. Furthermore it relates to an adsorbate comprising API being practically insoluble in water and to a process for the preparation of said adsorbate with non-polar solvent (s) such as chlorinated hydrocarbon, diisopropylethes and hexane. Furthermore the invention relates to a process for the preparation of the dosage form, as well as to the use of the adsorbate for the preparation of the dosage form. Moreover it relates to the dosage form for use in the treatment of erectile dysfunction, human immunodeficiency virus (HIV) infections and/or Acquired Immune Deficiency Syndrome (AIDS).
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title ACTIVE PHARMACEUTICAL INGREDIENT ADSORBED ON SOLID SUPPORT
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