NOVEL SOLVATE AND CRYSTALLINE FORMS OF CARBAMOYL-CYCLOHEXANE DERIVATIVES

The present invention relates to novel solvate and crystalline forms of carbamoyl-cyclohexane derivatives and, more particularly, to novel solvate and crystalline forms of trans-1{4-[2-[4-(2,3-dichlorophenyl)-piperazin-1-yl]- ethyl]--cyclohexyl}-3,3-dimethyl-urea hydrochloride. Processes for the pre...

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Bibliographische Detailangaben
Hauptverfasser:	ZHU, HAIJIAN, LIAO, XIANGMIN, GRILL, ANDREAS
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to novel solvate and crystalline forms of carbamoyl-cyclohexane derivatives and, more particularly, to novel solvate and crystalline forms of trans-1{4-[2-[4-(2,3-dichlorophenyl)-piperazin-1-yl]- ethyl]--cyclohexyl}-3,3-dimethyl-urea hydrochloride. Processes for the preparation of these forms, compositions containing these forms, and methods of use thereof are also described. La présente invention porte sur un nouveau solvate et des formes cristallines dérivés de carbomoyle-cyclohexane et, plus particulièrement sur le nouveau solvate et les formes cristallines de chlorhydrate de trans-l{4-[2-[4-(2,3-dichlorophényl)-pipérazin-1-yl]-éthyl]-cyclohexyl}-3,3-diméthyl-urée. Des procédés de préparation de ces formes, des compositions contenant ces formes, et des procédés dutilisation sont également décrits.