COLLAGEN-RELATED PEPTIDES AND USES THEREOF AND HEMOSTATIC FOAM SUBSTRATES
The present invention relates to a collagen-related polypeptide (CRP) having hydrophobic amino acid groups at the N- and C-termini capable of non-covalent self-assembly into collagen mimetic triple helices and fibrils thereof and the synthesis, methods of use and compositions thereof. The present in...
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| creator | JOHN, THOPPIL MATHEW YANG, CHUNLIN MATALENAS, THOMAS |
| description | The present invention relates to a collagen-related polypeptide (CRP) having hydrophobic amino acid groups at the N- and C-termini capable of non-covalent self-assembly into collagen mimetic triple helices and fibrils thereof and the synthesis, methods of use and compositions thereof. The present invention also relates to novel hemostatic foam substrates, a method of manufacturing the foam substrates, and a method of stimulating hemostasis in a mammal using such foam substrates.
La présente invention concerne un polypeptide lié au collagène (CRP) présentant des groupes d'acides aminés hydrophobes aux extrémités N- et C-terminales pouvant s'auto-assembler de manière non covalente en triples hélices mimétiques du collagène et en fibrilles de celui-ci, ainsi que la synthèse, des procédés d'utilisation et des compositions associés. La présente invention concerne également de nouveaux substrats en mousse hémostatiques, un procédé de fabrication des substrats en mousse, et un procédé permettant de stimuler l'hémostase chez un mammifère à l'aide de tels substrats en mousse. |
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La présente invention concerne un polypeptide lié au collagène (CRP) présentant des groupes d'acides aminés hydrophobes aux extrémités N- et C-terminales pouvant s'auto-assembler de manière non covalente en triples hélices mimétiques du collagène et en fibrilles de celui-ci, ainsi que la synthèse, des procédés d'utilisation et des compositions associés. La présente invention concerne également de nouveaux substrats en mousse hémostatiques, un procédé de fabrication des substrats en mousse, et un procédé permettant de stimuler l'hémostase chez un mammifère à l'aide de tels substrats en mousse.</description><language>eng ; fre</language><subject>CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES ; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR ; HUMAN NECESSITIES ; HYGIENE ; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES ; MEDICAL OR VETERINARY SCIENCE ; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL</subject><creationdate>2017</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20171212&DB=EPODOC&CC=CA&NR=2751132C$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20171212&DB=EPODOC&CC=CA&NR=2751132C$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>JOHN, THOPPIL MATHEW</creatorcontrib><creatorcontrib>YANG, CHUNLIN</creatorcontrib><creatorcontrib>MATALENAS, THOMAS</creatorcontrib><title>COLLAGEN-RELATED PEPTIDES AND USES THEREOF AND HEMOSTATIC FOAM SUBSTRATES</title><description>The present invention relates to a collagen-related polypeptide (CRP) having hydrophobic amino acid groups at the N- and C-termini capable of non-covalent self-assembly into collagen mimetic triple helices and fibrils thereof and the synthesis, methods of use and compositions thereof. The present invention also relates to novel hemostatic foam substrates, a method of manufacturing the foam substrates, and a method of stimulating hemostasis in a mammal using such foam substrates.
La présente invention concerne un polypeptide lié au collagène (CRP) présentant des groupes d'acides aminés hydrophobes aux extrémités N- et C-terminales pouvant s'auto-assembler de manière non covalente en triples hélices mimétiques du collagène et en fibrilles de celui-ci, ainsi que la synthèse, des procédés d'utilisation et des compositions associés. La présente invention concerne également de nouveaux substrats en mousse hémostatiques, un procédé de fabrication des substrats en mousse, et un procédé permettant de stimuler l'hémostase chez un mammifère à l'aide de tels substrats en mousse.</description><subject>CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES</subject><subject>DISINFECTION, STERILISATION, OR DEODORISATION OF AIR</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2017</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZPB09vfxcXR39dMNcvVxDHF1UQhwDQjxdHENVnD0c1EIDQYyQjxcg1z93cACHq6-_sEhjiGezgpu_o6-CsGhTsEhQUCNwTwMrGmJOcWpvFCam0HezTXE2UM3tSA_PrW4IDE5NS-1JN7Z0cjc1NDQ2MjZmLAKAHqfLCg</recordid><startdate>20171212</startdate><enddate>20171212</enddate><creator>JOHN, THOPPIL MATHEW</creator><creator>YANG, CHUNLIN</creator><creator>MATALENAS, THOMAS</creator><scope>EVB</scope></search><sort><creationdate>20171212</creationdate><title>COLLAGEN-RELATED PEPTIDES AND USES THEREOF AND HEMOSTATIC FOAM SUBSTRATES</title><author>JOHN, THOPPIL MATHEW ; YANG, CHUNLIN ; MATALENAS, THOMAS</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CA2751132C3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2017</creationdate><topic>CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES</topic><topic>DISINFECTION, STERILISATION, OR DEODORISATION OF AIR</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL</topic><toplevel>online_resources</toplevel><creatorcontrib>JOHN, THOPPIL MATHEW</creatorcontrib><creatorcontrib>YANG, CHUNLIN</creatorcontrib><creatorcontrib>MATALENAS, THOMAS</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>JOHN, THOPPIL MATHEW</au><au>YANG, CHUNLIN</au><au>MATALENAS, THOMAS</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>COLLAGEN-RELATED PEPTIDES AND USES THEREOF AND HEMOSTATIC FOAM SUBSTRATES</title><date>2017-12-12</date><risdate>2017</risdate><abstract>The present invention relates to a collagen-related polypeptide (CRP) having hydrophobic amino acid groups at the N- and C-termini capable of non-covalent self-assembly into collagen mimetic triple helices and fibrils thereof and the synthesis, methods of use and compositions thereof. The present invention also relates to novel hemostatic foam substrates, a method of manufacturing the foam substrates, and a method of stimulating hemostasis in a mammal using such foam substrates.
La présente invention concerne un polypeptide lié au collagène (CRP) présentant des groupes d'acides aminés hydrophobes aux extrémités N- et C-terminales pouvant s'auto-assembler de manière non covalente en triples hélices mimétiques du collagène et en fibrilles de celui-ci, ainsi que la synthèse, des procédés d'utilisation et des compositions associés. La présente invention concerne également de nouveaux substrats en mousse hémostatiques, un procédé de fabrication des substrats en mousse, et un procédé permettant de stimuler l'hémostase chez un mammifère à l'aide de tels substrats en mousse.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES DISINFECTION, STERILISATION, OR DEODORISATION OF AIR HUMAN NECESSITIES HYGIENE MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL |
| title | COLLAGEN-RELATED PEPTIDES AND USES THEREOF AND HEMOSTATIC FOAM SUBSTRATES |
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