NOVEL ANTIBACTERIAL AGENTS FOR THE TREATMENT OF GRAM POSITIVE INFECTIONS

The present invention relates to novel lipopeptide compounds, pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The compounds of the invention are particularly useful against a variety of bacteria, including resistant strains. The compoun...

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Bibliographische Detailangaben
Hauptverfasser:	PEARSON, ANDRE LEE, METCALF, CHESTER A., III, LI, JING
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY METALLURGY ORGANIC CHEMISTRY PEPTIDES
Online-Zugang:	Volltext bestellen
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Beschreibung
Zusammenfassung:	The present invention relates to novel lipopeptide compounds, pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The compounds of the invention are particularly useful against a variety of bacteria, including resistant strains. The compounds are useful as antibacterial agents against Clostridium difficile. L'invention porte sur de nouveaux composés lipopeptidiques, sur des compositions pharmaceutiques de ces composés et sur des procédés d'utilisation de ces composés en tant que composés antibactériens. Les composés de l'invention sont particulièrement utiles contre une pluralité de bactéries, comprenant des souches résistantes. Les composés sont utiles en tant qu'agents antibactériens contre Clostridium difficile.