ANTI-CMET ANTIBODY
Antibody capable of binding specifically to the human c-Met receptor and/or capable of specifically inhibiting the tyrosine kinase activity of said receptor, with an improved antagonistic activity, said antibody comprising a modified hinge region. A composition comprising such an antibody antagonist...
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| creator | BES, CEDRIC WURCH, THIERRY GOETSCH, LILIANE |
| description | Antibody capable of binding specifically to the human c-Met receptor and/or capable of specifically inhibiting the tyrosine kinase activity of said receptor, with an improved antagonistic activity, said antibody comprising a modified hinge region. A composition comprising such an antibody antagonist to c-Met and its use as a medicament for treating cancer.
L'invention concerne un anticorps capable de se lier spécifiquement au récepteur c-MET humain et/ou d'inhiber spécifiquement l'activité de tyrosine kinase dudit récepteur, avec une meilleure activité antagoniste, ledit anticorps comprenant une zone charnière modifiée. L'invention concerne également une composition comprenant un tel anticorps antagoniste de c-MET et son utilisation comme médicament pour le traitement du cancer. |
| format | Patent |
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L'invention concerne un anticorps capable de se lier spécifiquement au récepteur c-MET humain et/ou d'inhiber spécifiquement l'activité de tyrosine kinase dudit récepteur, avec une meilleure activité antagoniste, ledit anticorps comprenant une zone charnière modifiée. L'invention concerne également une composition comprenant un tel anticorps antagoniste de c-MET et son utilisation comme médicament pour le traitement du cancer.</description><language>eng ; fre</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2019</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20190611&DB=EPODOC&CC=CA&NR=2743433C$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,778,883,25547,76298</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20190611&DB=EPODOC&CC=CA&NR=2743433C$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>BES, CEDRIC</creatorcontrib><creatorcontrib>WURCH, THIERRY</creatorcontrib><creatorcontrib>GOETSCH, LILIANE</creatorcontrib><title>ANTI-CMET ANTIBODY</title><description>Antibody capable of binding specifically to the human c-Met receptor and/or capable of specifically inhibiting the tyrosine kinase activity of said receptor, with an improved antagonistic activity, said antibody comprising a modified hinge region. A composition comprising such an antibody antagonist to c-Met and its use as a medicament for treating cancer.
L'invention concerne un anticorps capable de se lier spécifiquement au récepteur c-MET humain et/ou d'inhiber spécifiquement l'activité de tyrosine kinase dudit récepteur, avec une meilleure activité antagoniste, ledit anticorps comprenant une zone charnière modifiée. L'invention concerne également une composition comprenant un tel anticorps antagoniste de c-MET et son utilisation comme médicament pour le traitement du cancer.</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2019</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZBBy9Avx1HX2dQ1RALGc_F0ieRhY0xJzilN5oTQ3g7yba4izh25qQX58anFBYnJqXmpJvLOjkbmJsYmxsbMxYRUAwO0dDw</recordid><startdate>20190611</startdate><enddate>20190611</enddate><creator>BES, CEDRIC</creator><creator>WURCH, THIERRY</creator><creator>GOETSCH, LILIANE</creator><scope>EVB</scope></search><sort><creationdate>20190611</creationdate><title>ANTI-CMET ANTIBODY</title><author>BES, CEDRIC ; WURCH, THIERRY ; GOETSCH, LILIANE</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CA2743433C3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2019</creationdate><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>BES, CEDRIC</creatorcontrib><creatorcontrib>WURCH, THIERRY</creatorcontrib><creatorcontrib>GOETSCH, LILIANE</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>BES, CEDRIC</au><au>WURCH, THIERRY</au><au>GOETSCH, LILIANE</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>ANTI-CMET ANTIBODY</title><date>2019-06-11</date><risdate>2019</risdate><abstract>Antibody capable of binding specifically to the human c-Met receptor and/or capable of specifically inhibiting the tyrosine kinase activity of said receptor, with an improved antagonistic activity, said antibody comprising a modified hinge region. A composition comprising such an antibody antagonist to c-Met and its use as a medicament for treating cancer.
L'invention concerne un anticorps capable de se lier spécifiquement au récepteur c-MET humain et/ou d'inhiber spécifiquement l'activité de tyrosine kinase dudit récepteur, avec une meilleure activité antagoniste, ledit anticorps comprenant une zone charnière modifiée. L'invention concerne également une composition comprenant un tel anticorps antagoniste de c-MET et son utilisation comme médicament pour le traitement du cancer.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | ANTI-CMET ANTIBODY |
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