ANTIFUNGAL AGENTS

Novel derivatives of enfumafungin are disclosed herein, along with their pharmaceutically acceptable salts, hydrates and prodrugs. Also disclosed are compositions comprising such compounds, methods of preparing such compounds and methods of using such compounds as antifungal agents and/or inhibitors...

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Hauptverfasser: MAMAI, AHMED, NELSON, KINGSLEY, WILDONGER, KENNETH JAMES, SPERBECK, DONALD, HEASLEY, BRIAN HAID, PACOFSKY, GREGORY JAMES, WILKENING, ROBERT, MENG, DONGFANG, GREENLEE, MARK L, APGAR, JAMES, PARKER, DANN L
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creator MAMAI, AHMED
NELSON, KINGSLEY
WILDONGER, KENNETH JAMES
SPERBECK, DONALD
HEASLEY, BRIAN HAID
PACOFSKY, GREGORY JAMES
WILKENING, ROBERT
MENG, DONGFANG
GREENLEE, MARK L
APGAR, JAMES
PARKER, DANN L
description Novel derivatives of enfumafungin are disclosed herein, along with their pharmaceutically acceptable salts, hydrates and prodrugs. Also disclosed are compositions comprising such compounds, methods of preparing such compounds and methods of using such compounds as antifungal agents and/or inhibitors of (l,3)-ß-D-glucan synthase. The disclosed compounds, their pharmaceutically acceptable salts, hydrates and prodrugs,,as well as compositions comprising such compounds, salts, hydrates and prodrugs, are useful for treating and/or preventing fungal infections and associated diseases and conditions.
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Also disclosed are compositions comprising such compounds, methods of preparing such compounds and methods of using such compounds as antifungal agents and/or inhibitors of (l,3)-ß-D-glucan synthase. 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subjects AGRICULTURE
ANIMAL HUSBANDRY
BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES
FISHING
FORESTRY
HUMAN NECESSITIES
HUNTING
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PEST REPELLANTS OR ATTRACTANTS
PLANT GROWTH REGULATORS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF
TRAPPING
title ANTIFUNGAL AGENTS
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