FOSAPREPITANT DIMEGLUMINE INTERMEDIATE, NEUTRAL FOSAPREPITANT, AND AMORPHOUS FOSAPREPITANT DIMEGLUMINE AND PROCESSES FOR THEIR PREPARATIONS

The present invention generally relates to a process for the preparation of fosaprepitant dimeglumine intermediate and its use in the preparation of fosaprepitant dimeglumine; to a neutral form of fosaprepitant in a solid state and processes for the preparation thereof; and to a stable amorphous fos...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: YADAV, RAMJILAL, GANESHBHATT, NAVIN, RASIKLALTRIVEDI, NIKHIL, KHEDEKAR, MAHESH, SINHA, SUKUMAR, AHMED KHAN, MUBEEN
Format: Patent
Sprache:eng ; fre
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator YADAV, RAMJILAL
GANESHBHATT, NAVIN
RASIKLALTRIVEDI, NIKHIL
KHEDEKAR, MAHESH
SINHA, SUKUMAR
AHMED KHAN, MUBEEN
description The present invention generally relates to a process for the preparation of fosaprepitant dimeglumine intermediate and its use in the preparation of fosaprepitant dimeglumine; to a neutral form of fosaprepitant in a solid state and processes for the preparation thereof; and to a stable amorphous fosaprepitant dimeglumine, having a stability at temperatures of about 2°C to about 8°C and at a relative humidity below at least 60%; and a process for the preparation thereof (see formula II) De manière générale, la présente invention concerne un procédé pour la préparation d'un intermédiaire de fosaprépitant diméglumine et son utilisation dans la préparation de fosaprépitant diméglumine, une forme neutre de fosaprépitant à l'état solide et des procédés de préparation de celle-ci, ainsi qu'un fosaprépitant diméglumine amorphe stable, présentant une stabilité à des températures comprises entre environ 2°C et environ 8°C et à une humidité relative inférieure à au moins 60%, et un procédé de préparation correspondant.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_CA2730681C</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>CA2730681C</sourcerecordid><originalsourceid>FETCH-epo_espacenet_CA2730681C3</originalsourceid><addsrcrecordid>eNqFzD0KwkAQQOE0FqKewTlABDWgtsNmYgayP8xO6hBkrUQD8RZeWgI2FmL1mo83z16VjxiEAis6hZItnZvWsiNgpySWSkalHBy1KtjAl88BXQlovYTatxF-zyYXxBuKkSYnoDWxwKRRUNm7uMxm1_42ptWni2xdkZp6k4ZHl8ahv6R7enYG98diezjtTPFfvAGq8D8y</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>FOSAPREPITANT DIMEGLUMINE INTERMEDIATE, NEUTRAL FOSAPREPITANT, AND AMORPHOUS FOSAPREPITANT DIMEGLUMINE AND PROCESSES FOR THEIR PREPARATIONS</title><source>esp@cenet</source><creator>YADAV, RAMJILAL ; GANESHBHATT, NAVIN ; RASIKLALTRIVEDI, NIKHIL ; KHEDEKAR, MAHESH ; SINHA, SUKUMAR ; AHMED KHAN, MUBEEN</creator><creatorcontrib>YADAV, RAMJILAL ; GANESHBHATT, NAVIN ; RASIKLALTRIVEDI, NIKHIL ; KHEDEKAR, MAHESH ; SINHA, SUKUMAR ; AHMED KHAN, MUBEEN</creatorcontrib><description>The present invention generally relates to a process for the preparation of fosaprepitant dimeglumine intermediate and its use in the preparation of fosaprepitant dimeglumine; to a neutral form of fosaprepitant in a solid state and processes for the preparation thereof; and to a stable amorphous fosaprepitant dimeglumine, having a stability at temperatures of about 2°C to about 8°C and at a relative humidity below at least 60%; and a process for the preparation thereof (see formula II) De manière générale, la présente invention concerne un procédé pour la préparation d'un intermédiaire de fosaprépitant diméglumine et son utilisation dans la préparation de fosaprépitant diméglumine, une forme neutre de fosaprépitant à l'état solide et des procédés de préparation de celle-ci, ainsi qu'un fosaprépitant diméglumine amorphe stable, présentant une stabilité à des températures comprises entre environ 2°C et environ 8°C et à une humidité relative inférieure à au moins 60%, et un procédé de préparation correspondant.</description><language>eng ; fre</language><subject>ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM ; CHEMISTRY ; METALLURGY ; ORGANIC CHEMISTRY</subject><creationdate>2017</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20170307&amp;DB=EPODOC&amp;CC=CA&amp;NR=2730681C$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20170307&amp;DB=EPODOC&amp;CC=CA&amp;NR=2730681C$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>YADAV, RAMJILAL</creatorcontrib><creatorcontrib>GANESHBHATT, NAVIN</creatorcontrib><creatorcontrib>RASIKLALTRIVEDI, NIKHIL</creatorcontrib><creatorcontrib>KHEDEKAR, MAHESH</creatorcontrib><creatorcontrib>SINHA, SUKUMAR</creatorcontrib><creatorcontrib>AHMED KHAN, MUBEEN</creatorcontrib><title>FOSAPREPITANT DIMEGLUMINE INTERMEDIATE, NEUTRAL FOSAPREPITANT, AND AMORPHOUS FOSAPREPITANT DIMEGLUMINE AND PROCESSES FOR THEIR PREPARATIONS</title><description>The present invention generally relates to a process for the preparation of fosaprepitant dimeglumine intermediate and its use in the preparation of fosaprepitant dimeglumine; to a neutral form of fosaprepitant in a solid state and processes for the preparation thereof; and to a stable amorphous fosaprepitant dimeglumine, having a stability at temperatures of about 2°C to about 8°C and at a relative humidity below at least 60%; and a process for the preparation thereof (see formula II) De manière générale, la présente invention concerne un procédé pour la préparation d'un intermédiaire de fosaprépitant diméglumine et son utilisation dans la préparation de fosaprépitant diméglumine, une forme neutre de fosaprépitant à l'état solide et des procédés de préparation de celle-ci, ainsi qu'un fosaprépitant diméglumine amorphe stable, présentant une stabilité à des températures comprises entre environ 2°C et environ 8°C et à une humidité relative inférieure à au moins 60%, et un procédé de préparation correspondant.</description><subject>ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM</subject><subject>CHEMISTRY</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2017</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqFzD0KwkAQQOE0FqKewTlABDWgtsNmYgayP8xO6hBkrUQD8RZeWgI2FmL1mo83z16VjxiEAis6hZItnZvWsiNgpySWSkalHBy1KtjAl88BXQlovYTatxF-zyYXxBuKkSYnoDWxwKRRUNm7uMxm1_42ptWni2xdkZp6k4ZHl8ahv6R7enYG98diezjtTPFfvAGq8D8y</recordid><startdate>20170307</startdate><enddate>20170307</enddate><creator>YADAV, RAMJILAL</creator><creator>GANESHBHATT, NAVIN</creator><creator>RASIKLALTRIVEDI, NIKHIL</creator><creator>KHEDEKAR, MAHESH</creator><creator>SINHA, SUKUMAR</creator><creator>AHMED KHAN, MUBEEN</creator><scope>EVB</scope></search><sort><creationdate>20170307</creationdate><title>FOSAPREPITANT DIMEGLUMINE INTERMEDIATE, NEUTRAL FOSAPREPITANT, AND AMORPHOUS FOSAPREPITANT DIMEGLUMINE AND PROCESSES FOR THEIR PREPARATIONS</title><author>YADAV, RAMJILAL ; GANESHBHATT, NAVIN ; RASIKLALTRIVEDI, NIKHIL ; KHEDEKAR, MAHESH ; SINHA, SUKUMAR ; AHMED KHAN, MUBEEN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CA2730681C3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2017</creationdate><topic>ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM</topic><topic>CHEMISTRY</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><toplevel>online_resources</toplevel><creatorcontrib>YADAV, RAMJILAL</creatorcontrib><creatorcontrib>GANESHBHATT, NAVIN</creatorcontrib><creatorcontrib>RASIKLALTRIVEDI, NIKHIL</creatorcontrib><creatorcontrib>KHEDEKAR, MAHESH</creatorcontrib><creatorcontrib>SINHA, SUKUMAR</creatorcontrib><creatorcontrib>AHMED KHAN, MUBEEN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>YADAV, RAMJILAL</au><au>GANESHBHATT, NAVIN</au><au>RASIKLALTRIVEDI, NIKHIL</au><au>KHEDEKAR, MAHESH</au><au>SINHA, SUKUMAR</au><au>AHMED KHAN, MUBEEN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>FOSAPREPITANT DIMEGLUMINE INTERMEDIATE, NEUTRAL FOSAPREPITANT, AND AMORPHOUS FOSAPREPITANT DIMEGLUMINE AND PROCESSES FOR THEIR PREPARATIONS</title><date>2017-03-07</date><risdate>2017</risdate><abstract>The present invention generally relates to a process for the preparation of fosaprepitant dimeglumine intermediate and its use in the preparation of fosaprepitant dimeglumine; to a neutral form of fosaprepitant in a solid state and processes for the preparation thereof; and to a stable amorphous fosaprepitant dimeglumine, having a stability at temperatures of about 2°C to about 8°C and at a relative humidity below at least 60%; and a process for the preparation thereof (see formula II) De manière générale, la présente invention concerne un procédé pour la préparation d'un intermédiaire de fosaprépitant diméglumine et son utilisation dans la préparation de fosaprépitant diméglumine, une forme neutre de fosaprépitant à l'état solide et des procédés de préparation de celle-ci, ainsi qu'un fosaprépitant diméglumine amorphe stable, présentant une stabilité à des températures comprises entre environ 2°C et environ 8°C et à une humidité relative inférieure à au moins 60%, et un procédé de préparation correspondant.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng ; fre
recordid cdi_epo_espacenet_CA2730681C
source esp@cenet
subjects ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
title FOSAPREPITANT DIMEGLUMINE INTERMEDIATE, NEUTRAL FOSAPREPITANT, AND AMORPHOUS FOSAPREPITANT DIMEGLUMINE AND PROCESSES FOR THEIR PREPARATIONS
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-04T17%3A11%3A32IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=YADAV,%20RAMJILAL&rft.date=2017-03-07&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3ECA2730681C%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true