DIAMINO-PYRIDINE, PYRIMIDINE, AND PYRIDAZINE MODULATORS OF THE HISTAMINE H4 RECEPTOR

Diamino-pyridine, pyrimidine and pyridazine compounds which may be used as H4 receptor modulators, and in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by H4 receptor activity, such as allergy, asthma, autoimmune diseases, and pruriti...

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Hauptverfasser:	THURMOND, ROBIN L, GREENSPAN, ANDREW J, MEDUNA, STEVEN P, ZHANG, XIAOHU, DUNFORD, PAUL J, QUIROZ, JORGE A, CAI, HUI, SAVALL, BRAD M, WOLIN, RONALD L, CHAVEZ, FRANK, TAYS, KEVIN L, WEI, JIANMEI
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:	Diamino-pyridine, pyrimidine and pyridazine compounds which may be used as H4 receptor modulators, and in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by H4 receptor activity, such as allergy, asthma, autoimmune diseases, and pruritis. L'invention porte sur des composés diamino-pyridines, pyrimidines et pyridazines qui peuvent être utilisés comme modulateurs du récepteur H4, et sur des compositions pharmaceutiques et des procédés pour le traitement d'états morbides, de troubles et d'affections à médiation par l'activité du récepteur H4, tels qu'une allergie, l'asthme, des maladies auto-immunes et le prurit.