HEMOSTATIC MICROSPHERES

Provided herein are hemostatic compositions. In one embodiment, the hemostatic composition includes cross-linked polymer microspheres, such as cross-linked gelatin microspheres with pores. In another embodiment, the hemostatic composition comprises an additive such as a wetting agent, a suspending a...

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Bibliographische Detailangaben
Hauptverfasser: LASSER, GERALD W, MEYER, JEFFREY D, SENDEROFF, RICHARD I, GARCIA, RICHARD M, BISHOP, PAUL D, HUGHES, STEVEN D, ROLLINS, EMILY N
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:Provided herein are hemostatic compositions. In one embodiment, the hemostatic composition includes cross-linked polymer microspheres, such as cross-linked gelatin microspheres with pores. In another embodiment, the hemostatic composition comprises an additive such as a wetting agent, a suspending agent, or both. The hemostatic compositions may also include a hemostatic agent such as thrombin, and may include a high concentration of thrombin. The hemostatic compositions may also include plasma. Also provided herein are devices for dispersing said hemostatic compositions in a diluent, and delivering said dispersed hemostatic composition. The hemostatic compositions may also fabricated with a selected geometry as administration suggests.