CATIONIC SIRNAS, SYNTHESIS AND USE FOR INTERFERING RNA
L'invention se rapporte à des siRNA cationiques, caractérisés en ce qu'il s'agit de fragments d'ARN double brin, aux extrémités desquels sont greffés des oligocations, le nombre de charges cationiques greffées étant comparable ou supérieur à celui des charges anioniques portées p...
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| creator | PFENDER, NADEGE REMY, JEAN-SERGE KOTERA, MITSUHARU BEHR, JEAN-PAUL |
| description | L'invention se rapporte à des siRNA cationiques, caractérisés en ce qu'il s'agit de fragments d'ARN double brin, aux extrémités desquels sont greffés des oligocations, le nombre de charges cationiques greffées étant comparable ou supérieur à celui des charges anioniques portées par les phosphates internucléosidiques des brins d'ARN.
The invention relates to cationic siRNAs, characterized in that they are double-stranded RNA fragments, grafted to the ends of which are oligocations, the number of cationic charges grafted being comparable to or greater than that of the anionic charges carried by the internucleoside phosphates of the RNA strands. |
| format | Patent |
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The invention relates to cationic siRNAs, characterized in that they are double-stranded RNA fragments, grafted to the ends of which are oligocations, the number of cationic charges grafted being comparable to or greater than that of the anionic charges carried by the internucleoside phosphates of the RNA strands.</description><language>eng ; fre</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; DERIVATIVES THEREOF ; ENZYMOLOGY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; NUCLEIC ACIDS ; NUCLEOSIDES ; NUCLEOTIDES ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; SUGARS ; VINEGAR ; WINE</subject><creationdate>2009</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20090806&DB=EPODOC&CC=CA&NR=2713075A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20090806&DB=EPODOC&CC=CA&NR=2713075A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>PFENDER, NADEGE</creatorcontrib><creatorcontrib>REMY, JEAN-SERGE</creatorcontrib><creatorcontrib>KOTERA, MITSUHARU</creatorcontrib><creatorcontrib>BEHR, JEAN-PAUL</creatorcontrib><title>CATIONIC SIRNAS, SYNTHESIS AND USE FOR INTERFERING RNA</title><description>L'invention se rapporte à des siRNA cationiques, caractérisés en ce qu'il s'agit de fragments d'ARN double brin, aux extrémités desquels sont greffés des oligocations, le nombre de charges cationiques greffées étant comparable ou supérieur à celui des charges anioniques portées par les phosphates internucléosidiques des brins d'ARN.
The invention relates to cationic siRNAs, characterized in that they are double-stranded RNA fragments, grafted to the ends of which are oligocations, the number of cationic charges grafted being comparable to or greater than that of the anionic charges carried by the internucleoside phosphates of the RNA strands.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>DERIVATIVES THEREOF</subject><subject>ENZYMOLOGY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>NUCLEIC ACIDS</subject><subject>NUCLEOSIDES</subject><subject>NUCLEOTIDES</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>SUGARS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2009</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDBzdgzx9PfzdFYI9gzycwzWUQiO9AvxcA32DFZw9HNRCA12VXDzD1Lw9AtxDXJzDfL0c1cAquNhYE1LzClO5YXS3AwKbq4hzh66qQX58anFBYnJqXmpJfHOjkbmhsYG5qaOhsZEKAEAu6gnSg</recordid><startdate>20090806</startdate><enddate>20090806</enddate><creator>PFENDER, NADEGE</creator><creator>REMY, JEAN-SERGE</creator><creator>KOTERA, MITSUHARU</creator><creator>BEHR, JEAN-PAUL</creator><scope>EVB</scope></search><sort><creationdate>20090806</creationdate><title>CATIONIC SIRNAS, SYNTHESIS AND USE FOR INTERFERING RNA</title><author>PFENDER, NADEGE ; REMY, JEAN-SERGE ; KOTERA, MITSUHARU ; BEHR, JEAN-PAUL</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CA2713075A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2009</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>DERIVATIVES THEREOF</topic><topic>ENZYMOLOGY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>NUCLEIC ACIDS</topic><topic>NUCLEOSIDES</topic><topic>NUCLEOTIDES</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>SUGARS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>PFENDER, NADEGE</creatorcontrib><creatorcontrib>REMY, JEAN-SERGE</creatorcontrib><creatorcontrib>KOTERA, MITSUHARU</creatorcontrib><creatorcontrib>BEHR, JEAN-PAUL</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>PFENDER, NADEGE</au><au>REMY, JEAN-SERGE</au><au>KOTERA, MITSUHARU</au><au>BEHR, JEAN-PAUL</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>CATIONIC SIRNAS, SYNTHESIS AND USE FOR INTERFERING RNA</title><date>2009-08-06</date><risdate>2009</risdate><abstract>L'invention se rapporte à des siRNA cationiques, caractérisés en ce qu'il s'agit de fragments d'ARN double brin, aux extrémités desquels sont greffés des oligocations, le nombre de charges cationiques greffées étant comparable ou supérieur à celui des charges anioniques portées par les phosphates internucléosidiques des brins d'ARN.
The invention relates to cationic siRNAs, characterized in that they are double-stranded RNA fragments, grafted to the ends of which are oligocations, the number of cationic charges grafted being comparable to or greater than that of the anionic charges carried by the internucleoside phosphates of the RNA strands.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA DERIVATIVES THEREOF ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS SUGARS VINEGAR WINE |
| title | CATIONIC SIRNAS, SYNTHESIS AND USE FOR INTERFERING RNA |
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