METHODS FOR INHIBITING SCARRING

The invention provides new methods of treatment using anti-scarring agents to inhibit scarring in humans, and also provides anti-scarring agents for new uses in the inhibition of scarring in humans. In a first incidence of treatment an anti-scarring agent is provided to each centimetre of a wound ma...

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Hauptverfasser: BOANAS, ADAM, O'KANE, SHARON, OWEN, KATE, NIELD, KERRY, FERGUSON, MARK WILLIAM JAMES, BUSH, JAMES, GOLDSPINK, NICHOLAS, SATTAR, ABDUL, OCCLESTON, NICHOLAS
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creator BOANAS, ADAM
O'KANE, SHARON
OWEN, KATE
NIELD, KERRY
FERGUSON, MARK WILLIAM JAMES
BUSH, JAMES
GOLDSPINK, NICHOLAS
SATTAR, ABDUL
OCCLESTON, NICHOLAS
description The invention provides new methods of treatment using anti-scarring agents to inhibit scarring in humans, and also provides anti-scarring agents for new uses in the inhibition of scarring in humans. In a first incidence of treatment an anti-scarring agent is provided to each centimetre of a wound margin or each centimetre of a site at which a wound is to be formed in a first therapeutically effective amount; and in a subsequent incidence of treatment the anti-scarring agent is provided to each centimetre of wound margin in a larger therapeutically effective amount. The incidences of treatment occur between 8 hours and 48 hours apart from one another. The anti-scarring agent is preferably not TGF-ß3. The anti-scarring agent may be provided by intradermal injection. Also provided are kits and methods of selecting an appropriate treatment regime for inhibiting scarring associated with the healing of a human wound.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title METHODS FOR INHIBITING SCARRING
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