PROCESS FOR PRODUCING RIBOFURANOSE DERIVATIVES

PROCESS FOR PRODUCING RIBOFURANOSE DERIVATIVES

The invention aims to provide a process for producing 1,2,3-tri-O-acetyl-5-deoxyribofuranose by an industrially suitable means. The invention provides a process for the production of 1,2,3-tri-O-acetyl-5-deoxyribofuranse which comprises hydrogenating a compound represented by the general formula (1)...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: MAEDA, TOMOKO, UEHARA, HISATOSHI, HARADA, NAOKI, KATSURADA, MANABU, SANO, MITSUHARU
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
DERIVATIVES THEREOF
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
SUGARS
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Beschreibung
Zusammenfassung:The invention aims to provide a process for producing 1,2,3-tri-O-acetyl-5-deoxyribofuranose by an industrially suitable means. The invention provides a process for the production of 1,2,3-tri-O-acetyl-5-deoxyribofuranse which comprises hydrogenating a compound represented by the general formula (1) or (2) in the presence of a metal catalyst: [wherein P1 and P2 are each independently hydrogen or acyl, or OP1 and OP2 may be united to form an acetal group; and R is hydrogen, alkyl, aryl, aralkyl or acyl][wherein X1 is Br or I; P3 and P4 are each independently hydrogen or acyl; and R is hydrogen, alkyl, aryl, aralkyl or acyl].