IRE-1A INHIBITORS

Compounds which directly inhibit IRE-la activity in vitro, prodrugs, and pharmaceutically acceptable salts thereof. Such compounds and prodrugs are useful for treating diseases associated with the unfolded protein response and can be used as single agents or in combination therapies.

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Hauptverfasser: PATTERSON, JOHN, BRUCE, LONERGAN, DAVID, GREGORY
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Sprache:eng ; fre
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creator PATTERSON, JOHN, BRUCE
LONERGAN, DAVID, GREGORY
description Compounds which directly inhibit IRE-la activity in vitro, prodrugs, and pharmaceutically acceptable salts thereof. Such compounds and prodrugs are useful for treating diseases associated with the unfolded protein response and can be used as single agents or in combination therapies.
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language eng ; fre
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title IRE-1A INHIBITORS
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