QUINOLINE DERIVATIVES AS PI3 KINASE INHIBITORS
Invented is a method of inhibiting the activity/function of PB kinases using quinoline derivatives of Formula I. Also invented is a method of treating one or more disease states selected from: autoimmune disorders, inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, allergy,...
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| creator | DARCY, MICHAEL GERARD NEWLANDER, KENNETH ALLEN BURGESS, JOELLE LORRAINE SARPONG, MARTHA DONATELLI, CARLA A RIDGERS, LANCE KNIGHT, STEVEN DAVID SCHMIDT, STANLEY J ADAMS, NICHOLAS D |
| description | Invented is a method of inhibiting the activity/function of PB kinases using quinoline derivatives of Formula I. Also invented is a method of treating one or more disease states selected from: autoimmune disorders, inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, allergy, asthma, pancreatitis, multiorgan failure, kidney diseases, platelet aggregation, cancer, sperm motility, transplantation rejection, graft rejection and lung injuries by the administration of quinoline derivatives. (see formula I) |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | QUINOLINE DERIVATIVES AS PI3 KINASE INHIBITORS |
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