SALTS OF 3- (1H-IND0L-3-YL) -4- [2- (4-METHYL-PIPERAZIN-I-YL) -QUINAZOLIN-4-YL] -PYRROLE-2, 5-DI ONE

SALTS OF 3- (1H-IND0L-3-YL) -4- [2- (4-METHYL-PIPERAZIN-I-YL) -QUINAZOLIN-4-YL] -PYRROLE-2, 5-DI ONE

The invention provides acid addition salts of 3-(1.H.-indol-3-yl)-4-[2-(4 -methyl-piperazin-1-yl)-quinazolin-4-yl]-pyrrole-2,5-dione, crystalline form s thereof, processes for the preparation thereof, pharmaceutical composition s comprising them and uses thereof in therapeutic treatment.

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Bibliographische Detailangaben
Hauptverfasser: PAPOUTSAKIS, DIMITRIS, KARPINSKI, PIOTR, YOWELL, GUY
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The invention provides acid addition salts of 3-(1.H.-indol-3-yl)-4-[2-(4 -methyl-piperazin-1-yl)-quinazolin-4-yl]-pyrrole-2,5-dione, crystalline form s thereof, processes for the preparation thereof, pharmaceutical composition s comprising them and uses thereof in therapeutic treatment.