METHOD FOR PREPARING 4-[17.BETA.-METHOXY-17.ALPHA.-METHOXYMETHYL-3-OXOESTRA-4,9-DIEN-11.BETA.-YL]BENZALDEHYDE (E)-OXIME (ASOPRISNIL)

The present invention relates to a method for the reliable and reproducible preparation of 4-[17.beta.-methoxy-17.alpha.-methoxymethyl-3-oxoestra-4,9-dien-ll.beta.- yl]benzaldehyde (E)-oxime (asoprisnil) on the pilot and manufacturing scale. Asoprisnil, which is prepared by this method, is distingui...

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Hauptverfasser: VOIGTLAENDER, DAVID, MOSEBACH, MICHAEL, GERECKE, HAGEN, EILERS, ROBERT, KNABE, UWE, TILSTAM, ULF, JACKE, JUERGEN, GLIESING, SABINE, WEHMEIER, DIETER, BOHLMANN, ULF, MUELLER, UWE, HOESEL, PETER, MICHEL, THOMAS, BAHL, KLAUS, SANDER, MICHAEL, GRAWE, DETLEF, ERHART, BERND
Format: Patent
Sprache:eng ; fre
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