GLUCOKINASE ACTIVATORS
Provided are compounds of formula I wherein R2, L, Z, Y, G and R1 are as defined herein, that are useful in the treatment and/or prevention of diseases or disorders mediated by deficient levels of glucokinase activity or which can be treated by activating glucokinase including, but not limited to, d...
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| creator | TURNER, TIMOTHY MARK SINGH, AJAY CONDROSKI, KEVIN RONALD AICHER, THOMAS DANIEL HINKLIN, RONALD J RUSTAM, FERDINAND GARREY CHICARELLI, MARK JOSEPH BOYD, STEVEN ARMEN |
| description | Provided are compounds of formula I wherein R2, L, Z, Y, G and R1 are as defined herein, that are useful in the treatment and/or prevention of diseases or disorders mediated by deficient levels of glucokinase activity or which can be treated by activating glucokinase including, but not limited to, diabetes mellitus, impaired glucose tolerance, IFG (impaired fasting glucose) and IFG (impaired fasting glycemia), as well as other diseases and disorders such as those discussed herein. |
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BOYD, STEVEN ARMEN</creatorcontrib><description>Provided are compounds of formula I wherein R2, L, Z, Y, G and R1 are as defined herein, that are useful in the treatment and/or prevention of diseases or disorders mediated by deficient levels of glucokinase activity or which can be treated by activating glucokinase including, but not limited to, diabetes mellitus, impaired glucose tolerance, IFG (impaired fasting glucose) and IFG (impaired fasting glycemia), as well as other diseases and disorders such as those discussed herein.</description><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2007</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20070809&DB=EPODOC&CC=CA&NR=2637172A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20070809&DB=EPODOC&CC=CA&NR=2637172A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>TURNER, TIMOTHY MARK</creatorcontrib><creatorcontrib>SINGH, AJAY</creatorcontrib><creatorcontrib>CONDROSKI, KEVIN RONALD</creatorcontrib><creatorcontrib>AICHER, THOMAS DANIEL</creatorcontrib><creatorcontrib>HINKLIN, RONALD J</creatorcontrib><creatorcontrib>RUSTAM, FERDINAND GARREY</creatorcontrib><creatorcontrib>CHICARELLI, MARK JOSEPH</creatorcontrib><creatorcontrib>BOYD, STEVEN ARMEN</creatorcontrib><title>GLUCOKINASE ACTIVATORS</title><description>Provided are compounds of formula I wherein R2, L, Z, Y, G and R1 are as defined herein, that are useful in the treatment and/or prevention of diseases or disorders mediated by deficient levels of glucokinase activity or which can be treated by activating glucokinase including, but not limited to, diabetes mellitus, impaired glucose tolerance, IFG (impaired fasting glucose) and IFG (impaired fasting glycemia), as well as other diseases and disorders such as those discussed herein.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2007</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZBBz9wl19vf29HMMdlVwdA7xDHMM8Q8K5mFgTUvMKU7lhdLcDApuriHOHrqpBfnxqcUFicmpeakl8c6ORmbG5obmRo6GxkQoAQCIPR7Q</recordid><startdate>20070809</startdate><enddate>20070809</enddate><creator>TURNER, TIMOTHY MARK</creator><creator>SINGH, AJAY</creator><creator>CONDROSKI, KEVIN RONALD</creator><creator>AICHER, THOMAS DANIEL</creator><creator>HINKLIN, RONALD J</creator><creator>RUSTAM, FERDINAND GARREY</creator><creator>CHICARELLI, MARK JOSEPH</creator><creator>BOYD, STEVEN ARMEN</creator><scope>EVB</scope></search><sort><creationdate>20070809</creationdate><title>GLUCOKINASE ACTIVATORS</title><author>TURNER, TIMOTHY MARK ; 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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | GLUCOKINASE ACTIVATORS |
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