ANTIBODY-DRUG CONJUGATES AND METHODS OF USE

The present disclosure provides antibody-drug conjugates that are potent cytotoxins, wherein the drug is linked to the antibody through a linker. The disclosure is also directed to compositions containing the antibody-drug conjugates, and to methods of treatment using them.

Bibliographische Detailangaben

Hauptverfasser:	PAN, CHIN, CHEN, LIANG, KING, DAVID JOHN, GUERLAVAIS, VINCENT, BOYD, SHARON ELAINE, HORGAN, KILIAN, HUANG, HAICHUN, SUFI, BILAL, GANGWAR, SANJEEV, CARDARELLI, JOSEPHINE M
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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