NOVEL CYCLOHEXENONE COMPOUNDS FROM ANTRODIA CAMPHORATA AND APPLICATION THEREOF

The present invention relates to a novel compound and its uses, which is an extract isolated and purified from Antrodia camphorata, in particular to 4-hydroxy--2,3-dimethoxy-6-methy-5(3,7,11-trimethyl-dodeca-2,6,10-trienyl)-cyclohex-2-enone, and its use in tumor growth inhibition. The compound of th...

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Hauptverfasser:	KUO, MAO-TIEN, FOK, KA-HANG, WEN, WU, HUANG, CHUN-HUNG, TSOU, WAN-LING, LIU, SHENG-YUN, LI, YA-YING, CHANG, CHUNGOU
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS BEER BIOCHEMISTRY CHEMISTRY ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to a novel compound and its uses, which is an extract isolated and purified from Antrodia camphorata, in particular to 4-hydroxy--2,3-dimethoxy-6-methy-5(3,7,11-trimethyl-dodeca-2,6,10-trienyl)-cyclohex-2-enone, and its use in tumor growth inhibition. The compound of the invention, which has never been discovered in Antrodia camphorata, can be applied in inhibiting the growth of cancer cells, such as breast cancer, hepatic cancer and prostate cancer; and be used as a pharmaceutical composition to inhibit the tumor growth; or further be applied in prevention of heart and blood vessel disease or dietary supplements for health needs through its antioxidant activity. La présente invention concerne un nouveau composé et ses utilisations, lequel est un extrait isolé et purifié à partir de Antrodia camphorata , à savoir la 4-hydroxy-2,3-diméthoxy-6-méthy-5(3,7,11-triméthyl-dodéca-2,6,10-triényl)-cyclohex-2-énone, et son utilisation pour inhiber la croissance des tumeurs. Parmi les applications éventuelles du composé de l'invention, lequel n'avait jamais été découvert chez Antrodia camphorata , figurent l'inhibition de la prolifération des cellules cancéreuses, comme celles du cancer du sein, du foie et de la prostate, son utilisation en tant que composition pharmaceutique pour inhiber la croissance tumorale et son utilisation pour prévenir des maladies cardiaques et des maladies des vaisseaux sanguins ou comme supplément alimentaire pour répondre à des besoins de santé étant donné son activité antioxydante.