PROCESS FOR CONVERTING AN ALCOHOL TO THE CORRESPONDING FLUORIDE

The invention provides a process for preparing a fluoride from its corresponding alcohol comprising the steps of (a) forming a mixture comprising (i) at least one primary or secondary alcohol and (ii) a molar excess of at least one strong, aprotic, non-nucleophilic, hindered, double bond--containing...

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Hauptverfasser: SNUSTAD, DANIEL C, SAVU, PATRICIA M
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creator SNUSTAD, DANIEL C
SAVU, PATRICIA M
description The invention provides a process for preparing a fluoride from its corresponding alcohol comprising the steps of (a) forming a mixture comprising (i) at least one primary or secondary alcohol and (ii) a molar excess of at least one strong, aprotic, non-nucleophilic, hindered, double bond--containing, organic base, said molar excess being less than 2 equivalents of said base per equivalent of said alcohol; and (b) adding at least one fluorinated, saturated aliphatic or alicyclic sulfonyl fluoride to said mixture.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
APPARATUS THEREFOR
CHEMISTRY
GENERAL METHODS OF ORGANIC CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title PROCESS FOR CONVERTING AN ALCOHOL TO THE CORRESPONDING FLUORIDE
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